Klebsiella pneumoniae subsp. pneumoniae strain 76

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain 76 is a Gram-negative, rod-shaped bacterium known for its role in causing pneumonia, specifically community-acquired pneumonia (CAP). This strain is classified as a chemoheterotroph, indicating it derives its energy from organic compounds. It exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. In terms of morphology, Klebsiella pneumoniae 76 can be found in various arrangements, including chains, pairs, and as single cells. The bacterium possesses flagella, providing it with mobility, which can facilitate its movement within host-associated habitats. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range, which is typical for many pathogenic organisms that infect warm-blooded hosts. Klebsiella pneumoniae 76 has a biotic relationship categorized as free-living, and it does not form spores. Its cellular structure includes two membranes and a single replicon, characteristics that are common among members of the Enterobacteriaceae family. The ecological role of Klebsiella pneumoniae subsp. pneumoniae strain 76 highlights its capacity to thrive in host-associated environments while also demonstrating mobility and adaptability. These traits enable the bacterium to colonize various niches within the host and potentially contribute to its pathogenicity, particularly in respiratory infections. Understanding these characteristics can provide insights into the bacterium's behavior and its implications for public health, especially in the context of pneumonia outbreaks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain 76

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain 76
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain 76

Gene Summary

Adenine Count

1240990 bp

Thymine Count

1240365 bp

Guanine Count

1636340 bp

Cytosine Count

1646889 bp

Genome Length

5764584 bp

Protein-coding Genes

5406 genes

Non-Coding Genes

298 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4-oxalomesaconate tautomeraseE9165_22170Not AvailableNegative4485416 - 448650138153.0
4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylaseE9165_22175Not AvailableNegative4486502 - 448721525879.3
4-oxalmesaconate hydrataseE9165_22180Not AvailableNegative4487212 - 448795227775.0
lysr family transcriptional regulatorE9165_22185Not AvailablePositive4488080 - 448930644925.6
gallate dioxygenaseE9165_22190Not AvailableNegative4489303 - 449056547149.2
mfs transporterE9165_22195Not AvailableNegative4490579 - 449194948806.1
laci family transcriptional regulatorE9165_22200Not AvailableNegative4492161 - 449310234152.9
pts sugar transporter subunit iibE9165_22205Not AvailablePositive4493396 - 449371011577.2
pts cellobiose transporter subunit iicE9165_22210Not AvailablePositive4493722 - 449504448198.3
pts lactose/cellobiose transporter subunit iiaE9165_22215Not AvailablePositive4495142 - 449544411331.6

Displaying genes 4391 – 4400 of 5704 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total