Klebsiella pneumoniae strain 75 GCID_CRE_0146_NODE_71

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 75 (GCID_CRE_0146_NODE_71) is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. It exhibits mobility due to the presence of flagella and typically forms arrangements of chains, pairs, and singles. This strain is mesophilic, thriving optimally at 37°C. K. pneumoniae strain 75 is associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other species across Metazoa, Viridiplantae, Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (domestic dogs), Amphibia (amphibians), and Equidae (horses). This wide host range indicates its adaptability and potential for cross-species transmission. Clinically, this strain is notably pathogenic to humans and is implicated in a variety of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis. The spectrum of infections it causes also includes intra-abdominal infections, wound infections, and neonatal sepsis. The ability to cause such a wide range of infections highlights its significance in both clinical settings and public health. Understanding the biological and ecological relationships of K. pneumoniae strain 75 is crucial, particularly given its free-living biotic relationship and its ability to thrive in host-associated environments. This adaptability may contribute to its pathogenicity and persistence in various ecological niches, emphasizing the importance of monitoring and controlling its spread in both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 75 GCID_CRE_0146_NODE_71

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 75 GCID_CRE_0146_NODE_71
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 75 GCID_CRE_0146_NODE_71, whole

Gene Summary

Adenine Count

1152950 bp

Thymine Count

1143809 bp

Guanine Count

1532582 bp

Cytosine Count

1562364 bp

Genome Length

5391705 bp

Protein-coding Genes

4991 genes

Non-Coding Genes

363 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
imidazole glycerol phosphate synthase subunit hishE9162_09235Not AvailablePositive1845472 - 184606221619.1
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomeraseE9162_09240Not AvailablePositive1846062 - 184679925981.2
imidazole glycerol phosphate synthase subunit hisfE9162_09245Not AvailablePositive1846781 - 184755728266.8
bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp diphosphatase hisieE9162_09250Not AvailablePositive1847551 - 184815022234.5
glycosyltransferaseE9162_09255Not AvailableNegative1848254 - 184957050223.6
glycosyltransferase family 1 proteinE9162_09260Not AvailableNegative1849693 - 185082642651.9
glycosyltransferaseE9162_09265Not AvailableNegative1850839 - 185173233924.2
udp-galactopyranose mutaseE9162_09270Not AvailableNegative1851729 - 185288344521.9
duf4422 domain-containing proteinE9162_09275Not AvailableNegative1852899 - 185479472921.9
o-antigen export system atp-binding protein rfbbE9162_09280Not AvailableNegative1854810 - 185555027447.7

Displaying genes 2171 – 2180 of 5354 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total