Bacteroides fragilis strain BFR_KZ01

Bacteroides fragilis strain BFR_KZ01 is a Gram-negative, rod-shaped, anaerobic bacterium classified as a chemoorganotroph. This strain is non-motile and typically exists as single cells, with a mesophilic optimal growth temperature of 37°C. It possesses two membranes and has a single replicon. BFR_KZ01 is primarily found in host-associated habitats and exhibits a free-living biotic relationship. Its known hosts include Homo sapiens (humans), Gallus gallus (chickens), various Metazoa, Equidae (horses), and Serpentes (snakes). This broad host range suggests its ecological versatility and adaptability within different biological systems. Significantly, Bacteroides fragilis strain BFR_KZ01 is associated with a variety of health effects in humans, including bacteremia, abscesses, and several gastrointestinal conditions such as diarrhea and colitis. It has also been implicated in more severe health issues like colorectal cancer and septicemia. The strain’s pathogenicity underscores its role in human health, particularly in conditions involving local tissue infections and intra-abdominal abscesses. The presence of B. fragilis in the human microbiome can be both beneficial and detrimental, highlighting its dual role in health and disease. Its ability to thrive in anaerobic environments and interact with various hosts emphasizes the complexity of microbial interactions and their implications for both individual health and ecological dynamics.