Bacteroides fragilis strain BFR_KZ02

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain BFR_KZ02 is a Gram-negative, rod-shaped bacterium classified as a chemoorganotroph, utilizing organic compounds for energy. This strain is an anaerobe, thriving in environments devoid of oxygen, and is typically found as single cells rather than in clusters. BFR_KZ02 is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its various hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. This strain possesses a unique biotic relationship, as it is free-living yet associated with multiple hosts. Bacteroides fragilis is notable for its pathogenic potential in humans, being implicated in various health issues such as bacteremia, abscess formation, and colorectal cancer. It can contribute to severe conditions like septicemia, intraabdominal abscesses, and soft-tissue infections. The pathogenicity of this strain highlights its role in both health and disease, emphasizing its significance in the human microbiome. BFR_KZ02's structure includes two membranes and a single replicon, characteristic of its classification within the Bacteroides genus. Understanding the ecological role and health implications of Bacteroides fragilis strains like BFR_KZ02 is crucial, as they can influence host health, particularly in the context of intestinal microbiota balance and the potential for opportunistic infections. The bacterium's ability to establish itself in various hosts indicates its adaptability and relevance in microbial ecology.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain BFR_KZ02

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain BFR_KZ02
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain BFR_KZ02

Gene Summary

Adenine Count

1456606 bp

Thymine Count

1475458 bp

Guanine Count

1116964 bp

Cytosine Count

1099014 bp

Genome Length

5148042 bp

Protein-coding Genes

4095 genes

Non-Coding Genes

76 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinE7X03_00275Not AvailableNegative57555 - 5819925383.1
signal peptidase iE7X03_00280Not AvailableNegative58263 - 5919835797.1
s26 family signal peptidaseE7X03_00285Not AvailableNegative59206 - 6069057303.0
4-hydroxy-tetrahydrodipicolinate reductaseE7X03_00290Not AvailableNegative60695 - 6142326602.6
duf4348 domain-containing proteinE7X03_00300Not AvailablePositive62911 - 6343820019.3
pp_00061E7X03_00305Not AvailableNegative63632 - 64564Not Available
hypothetical proteinE7X03_00310Not AvailableNegative64571 - 6579145373.0
hypothetical proteinE7X03_00315Not AvailablePositive66022 - 6666324424.8
acyl-acp--udp-n-acetylglucosamine o-acyltransferaseE7X03_00320Not AvailableNegative66765 - 6753527928.6
tolc family proteinE7X03_00325Not AvailableNegative67555 - 6894650292.1

Displaying genes 71 – 80 of 4171 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total