Bacteroides fragilis strain BFR_KZ03

Bacteroides fragilis strain BFR_KZ03 is a Gram-negative, rod-shaped bacterium that thrives in anaerobic environments, making it a chemoorganotroph. This strain is predominantly found in host-associated habitats and has been identified in various hosts, including Homo sapiens, Gallus gallus, Metazoa, Equidae, and Serpentes. It exhibits a single-cell arrangement and lacks mobility despite having flagella, suggesting adaptation to its anaerobic niche. The optimal growth temperature for BFR_KZ03 is 37°C, placing it within the mesophilic temperature range. It possesses a unique cellular structure with two membranes and a single replicon. As a free-living organism, Bacteroides fragilis is well-known for its diverse role in human health and disease. This strain has been associated with a range of health effects, including bacteremia, abscess formation, and various gastrointestinal diseases such as diarrhea and colitis. Notably, it has been implicated in serious conditions like septicemia, colorectal cancer (CRC), and local tissue infections. The pathogenicity of B. fragilis in humans underscores its potential impact on health, particularly in immunocompromised individuals or those with disrupted gut microbiota. Ecologically, the presence of Bacteroides fragilis in diverse animal hosts highlights its role in microbial ecosystems and suggests its significance in gut health and disease dynamics across species. Its ability to thrive in anaerobic conditions and various hosts positions it as a crucial player in both human health and the broader microbiome context.