Klebsiella pneumoniae strain MGF010

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain MGF010 is a Gram-negative, rod-shaped bacterium that primarily exists in host-associated environments. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic conditions, with an optimal growth temperature of 37°C, indicating its mesophilic nature. This strain demonstrates mobility due to the presence of flagella and typically forms chains, pairs, or singles. As a chemoheterotroph, K. pneumoniae MGF010 derives its energy from organic compounds, which it utilizes in its free-living biotic relationships. It has been documented to infect a wide range of hosts, including Homo sapiens, various avian species, and several other vertebrates, illustrating its ecological versatility. The pathogenicity of K. pneumoniae MGF010 is significant, particularly in humans, where it can cause a variety of severe health conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is notably nonsporulating, which may influence its survival and transmission dynamics in clinical settings. Understanding the wide range of hosts and health effects associated with K. pneumoniae MGF010 highlights its ecological adaptability and potential impact on human and animal health. The strain's ability to thrive in diverse environments and cause serious infections emphasizes the importance of monitoring and studying this opportunistic pathogen within both clinical and environmental microbiology contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain MGF010

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain MGF010
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain MGF010 MGF010_contig137, whole genome

Gene Summary

Adenine Count

1133815 bp

Thymine Count

1137066 bp

Guanine Count

1529858 bp

Cytosine Count

1526639 bp

Genome Length

5327378 bp

Protein-coding Genes

5132 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer protein tranE6R63_26720Not AvailableNegative5314536 - 531516222624.9
type-f conjugative transfer system pilin assembly protein trbcE6R63_26725Not AvailableNegative5315221 - 53154809044.71
conjugal transfer protein tranE6R63_26730Not AvailableNegative5315481 - 531610722680.9
conjugal transfer protein trbcE6R63_26735Not AvailableNegative5316166 - 53164088554.23
elongation factor tuE6R63_26740Not AvailablePositive5316426 - 531735734446.5
conjugal transfer protein trahE6R63_26745Not AvailableNegative5317358 - 531826732850.1
conjugal transfer protein trahE6R63_26750Not AvailableNegative5318268 - 531917732897.3
is6-like element is26 family transposaseE6R63_26755Not AvailablePositive5319241 - 531994527896.9
hypothetical proteinE6R63_26765Not AvailablePositive5320902 - 53211749910.61
hypothetical proteinE6R63_26770Not AvailablePositive5321171 - 532146711259.3

Displaying genes 5191 – 5200 of 5214 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total