Streptococcus pyogenes strain emm1_S5

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes strain emm1_S5 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen environments, and it is non-motile, lacking flagella. Its optimal growth temperature is around 30°C, placing it within the mesophilic temperature range. S. pyogenes emm1_S5 is associated with a host environment, primarily affecting Homo sapiens and other Metazoa. It exhibits a free-living biotic relationship but is notably pathogenic to humans. The strain is linked to a wide array of health complications, including pneumonia, meningitis, necrotizing fasciitis, sepsis, and a variety of skin infections such as cellulitis, impetigo, and necrotizing soft tissue infections. It also contributes to serious conditions like streptococcal toxic shock syndrome (STSS) and acute rheumatic fever (ARF). The presence of a single membrane and one replicon indicates a simplistic cellular structure typical of many bacteria. Given its extensive pathogenic potential, S. pyogenes emm1_S5 plays a significant role in human health, often leading to severe infections that necessitate prompt medical intervention. The ecological insight from this bacterium’s characteristics suggests that its adaptability to host-associated environments and its pathogenicity contribute to its success as a human pathogen, highlighting the importance of understanding its biology for effective disease management.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
Strainstrain emm1_S5

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes strain emm1_S5
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pyogenes strain emm1_S5

Gene Summary

Adenine Count

553713 bp

Thymine Count

553607 bp

Guanine Count

347586 bp

Cytosine Count

341617 bp

Genome Length

1796532 bp

Protein-coding Genes

1585 genes

Non-Coding Genes

194 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l10E6A97_02445Not AvailablePositive489166 - 48966617566.3
50s ribosomal protein l7/l12E6A97_02450Not AvailablePositive489731 - 49009612256.6
ifn-response binding factor 1E6A97_02455Not AvailablePositive490626 - 49099414107.3
lantibiotic (srt) production proteinE6A97_02475Not AvailablePositive492330 - 49297725575.5
response regulator transcription factorE6A97_02480Not AvailablePositive493128 - 49381426929.7
hamp domain-containing histidine kinaseE6A97_02485Not AvailablePositive493807 - 49515351474.4
lantibiotic streptinE6A97_02490Not AvailablePositive495301 - 4954415219.29
atp-binding cassette domain-containing proteinE6A97_02495Not AvailablePositive495556 - 49617323467.7
lantibiotic protection abc transporter atp-binding proteinE6A97_02500Not AvailablePositive496255 - 49694425680.7
lantibiotic immunity abc transporter mute/epie family permease subunitE6A97_02505Not AvailablePositive496950 - 49769928477.4

Displaying genes 661 – 670 of 1779 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionCausesPMC11555966
Suppurative pharyngitisCausesPMC11555966
TonsillitisCausesPMC11555966
ScarlatinaCausesPMC11555966
Brain abscessCausesPMC11555966
Sterile-site infectionsCausesPMC11555966
Streptococcal toxic shock syndrome (stss)CausesPMC11735781
Necrotizing fasciitisCausesPMC11735781
MeningitisCausesPMC11735781
Acute rheumatic fever (arf)CausesPMC11735781

Displaying health effects 1 – 10 of 62 in total