Streptococcus pyogenes strain emm1_S5

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes strain emm1_S5 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen environments, and it is non-motile, lacking flagella. Its optimal growth temperature is around 30°C, placing it within the mesophilic temperature range. S. pyogenes emm1_S5 is associated with a host environment, primarily affecting Homo sapiens and other Metazoa. It exhibits a free-living biotic relationship but is notably pathogenic to humans. The strain is linked to a wide array of health complications, including pneumonia, meningitis, necrotizing fasciitis, sepsis, and a variety of skin infections such as cellulitis, impetigo, and necrotizing soft tissue infections. It also contributes to serious conditions like streptococcal toxic shock syndrome (STSS) and acute rheumatic fever (ARF). The presence of a single membrane and one replicon indicates a simplistic cellular structure typical of many bacteria. Given its extensive pathogenic potential, S. pyogenes emm1_S5 plays a significant role in human health, often leading to severe infections that necessitate prompt medical intervention. The ecological insight from this bacterium’s characteristics suggests that its adaptability to host-associated environments and its pathogenicity contribute to its success as a human pathogen, highlighting the importance of understanding its biology for effective disease management.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
Strainstrain emm1_S5

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes strain emm1_S5
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pyogenes strain emm1_S5

Gene Summary

Adenine Count

553713 bp

Thymine Count

553607 bp

Guanine Count

347586 bp

Cytosine Count

341617 bp

Genome Length

1796532 bp

Protein-coding Genes

1585 genes

Non-Coding Genes

194 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
competence protein comeE6A97_05900Not AvailablePositive1173271 - 117373216967.3
elongation factor pE6A97_05905Not AvailablePositive1173828 - 117438520468.4
asp23/gls24 family envelope stress response proteinE6A97_05910Not AvailablePositive1174431 - 117482014136.9
transcription antitermination factor nusbE6A97_05915Not AvailablePositive1174813 - 117526516908.1
laci family transcriptional regulatorE6A97_05920Not AvailableNegative1175406 - 117637135684.6
glycoside hydrolase family 32 proteinE6A97_05925Not AvailableNegative1176376 - 117781554427.0
pts beta-glucoside transporter subunit iibcaE6A97_05930Not AvailablePositive1178057 - 117994066282.8
endo-beta-n-acetylglucosaminidaseE6A97_05935Not AvailablePositive1180171 - 1183158111870.0
rok family proteinE6A97_05940Not AvailablePositive1183422 - 118430631099.0
mannose-6-phosphate isomerase, class iE6A97_05945Not AvailablePositive1184401 - 118535435617.3

Displaying genes 1291 – 1300 of 1779 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionCausesPMC11555966
Suppurative pharyngitisCausesPMC11555966
TonsillitisCausesPMC11555966
ScarlatinaCausesPMC11555966
Brain abscessCausesPMC11555966
Sterile-site infectionsCausesPMC11555966
Streptococcal toxic shock syndrome (stss)CausesPMC11735781
Necrotizing fasciitisCausesPMC11735781
MeningitisCausesPMC11735781
Acute rheumatic fever (arf)CausesPMC11735781

Displaying health effects 1 – 10 of 62 in total