Streptococcus pyogenes strain emm1_S14

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes strain emm1_S14 is a Gram-positive, non-motile coccus that typically arranges itself in chains or pairs. As a facultative anaerobe, it can survive in both aerobic and anaerobic environments. This strain is mesophilic, with an optimal growth temperature of 30°C. S. pyogenes is primarily host-associated, with known hosts including Homo sapiens and various metazoans. It is categorized as free-living, indicating its ability to live independently of host organisms, although it is primarily pathogenic in humans. This bacterium is associated with a wide range of health effects, including pneumonia, meningitis, sepsis, and several skin infections such as cellulitis and impetigo. Notable severe complications include necrotizing fasciitis and streptococcal toxic shock syndrome (STSS), which underscore its pathogenic potential. The strain has a single replicon and membrane, emphasizing its simple cellular structure. Given its pathogenicity, S. pyogenes strain emm1_S14 plays a significant role in human health, contributing to numerous infectious diseases. Ecologically, the presence of S. pyogenes in human populations suggests a complex interplay with host immune responses and microbial communities, where it can cause disease under certain conditions. Understanding its traits and pathogenic mechanisms is crucial for developing targeted interventions and treatments for infections caused by this bacterium.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
Strainstrain emm1_S14

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes strain emm1_S14
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus pyogenes strain emm1_S14

Gene Summary

Adenine Count

550378 bp

Thymine Count

554612 bp

Guanine Count

342772 bp

Cytosine Count

345254 bp

Genome Length

1793046 bp

Protein-coding Genes

1612 genes

Non-Coding Genes

164 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter atp-binding proteinE6A89_04030Not AvailablePositive805583 - 80746071194.9
hypothetical proteinE6A89_04035Not AvailablePositive807878 - 8080968356.37
peptide deformylaseE6A89_04040Not AvailablePositive808352 - 80876215804.4
bifunctional metallophosphatase/5'-nucleotidaseE6A89_04045Not AvailableNegative808844 - 81085673218.5
gtp pyrophosphokinase family proteinE6A89_04050Not AvailablePositive811076 - 81172625009.3
response regulator transcription factorE6A89_04055Not AvailablePositive811729 - 81239725056.3
hamp domain-containing histidine kinaseE6A89_04060Not AvailablePositive812406 - 81363846481.3
mevalonate kinaseE6A89_04065Not AvailablePositive813917 - 81481032145.2
diphosphomevalonate decarboxylaseE6A89_04070Not AvailablePositive814792 - 81573634757.5
phosphomevalonate kinaseE6A89_04075Not AvailablePositive815729 - 81673636691.5

Displaying genes 851 – 860 of 1776 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionCausesPMC11555966
Suppurative pharyngitisCausesPMC11555966
TonsillitisCausesPMC11555966
ScarlatinaCausesPMC11555966
Brain abscessCausesPMC11555966
Sterile-site infectionsCausesPMC11555966
Streptococcal toxic shock syndrome (stss)CausesPMC11735781
Necrotizing fasciitisCausesPMC11735781
MeningitisCausesPMC11735781
Acute rheumatic fever (arf)CausesPMC11735781

Displaying health effects 1 – 10 of 62 in total