Clostridium perfringens strain NM49_B9-7

Clostridium perfringens strain NM49_B9-7 is a Gram-positive, rod-shaped bacterium classified as an anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain is capable of mobility, facilitated by the presence of flagella, and can be found in various arrangements including pairs, singles, and chains. It is a chemoorganotroph, meaning it derives energy from organic compounds. The ecological niche of C. perfringens NM49_B9-7 is primarily host-associated, with a broad spectrum of potential hosts including Homo sapiens, various livestock species (e.g., Gallus gallus, Bos, Ovis aries, Sus scrofa, Canis lupus familiaris), as well as other Metazoa and Aves. The bacterium demonstrates a free-living biotic relationship, indicating its ability to survive independently in the environment. C. perfringens NM49_B9-7 is notably pathogenic to both humans and animals, associated with a wide range of health effects. These include severe gastrointestinal illnesses such as food poisoning, enteritis, and necrotizing enteritis, as well as systemic conditions like sepsis and liver abscesses. The strain has been implicated in various foodborne diseases and outbreaks, highlighting its relevance in public health. The presence of C. perfringens NM49_B9-7 in diverse hosts and its potential to cause significant health issues underscore its ecological importance and role in both animal and human health dynamics. Understanding its pathogenic mechanisms and host interactions is crucial for managing the risks associated with this opportunistic pathogen.