Escherichia coli strain KCJK8354

Escherichia coli strain KCJK8354 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is characterized by its ability to be motile, possessing flagella, and typically exists in pairs or as singles. It is mesophilic, with an optimal growth temperature of 37°C. E. coli KCJK8354 is primarily host-associated, demonstrating a broad range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), various mammals, and even some plants like Solanum lycopersicum (tomato). This diverse host range indicates the strain's ecological versatility and adaptability in different biological contexts. Clinically, E. coli strain KCJK8354 is associated with numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and various forms of sepsis. It can cause severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS), which underscores its pathogenic potential in humans and other animals. The strain is also implicated in foodborne infections and has been linked to complications such as renal failure and colon carcinogenesis. The presence of E. coli KCJK8354 in both human and animal hosts highlights its role in the epidemiology of infectious diseases, particularly those related to the gastrointestinal and urinary tracts. Its ability to thrive in diverse environments and its pathogenicity suggest it plays a significant role in health and disease dynamics within ecosystems involving both flora and fauna.