Escherichia coli strain KCJK8399

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8399 is a Gram-negative, rod-shaped bacterium that exhibits mobility through the presence of flagella. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic range. This strain is associated with a variety of hosts, including Homo sapiens, Gallus gallus, Bos taurus, various mammals, and even plants such as Solanum lycopersicum and Brassica oleracea var. italica. The strain has been identified as free-living, which allows it to inhabit diverse ecological niches, particularly those associated with warm-blooded vertebrates. E. coli KCJK8399 is linked to significant health impacts in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity highlights its ability to cause a wide array of clinical conditions, ranging from mild diarrhea to severe septicemia. The extensive list of potential hosts indicates that E. coli KCJK8399 plays a role in both health and disease across multiple species. This bacterium's versatility and pathogenic potential underscore its ecological significance, as it can affect not only individual host health but also broader population dynamics and disease transmission within ecosystems. The presence of E. coli in both human and animal hosts further emphasizes its importance in public health and microbiological studies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8399

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8399
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8399 NODE_230_length_203_cov_8.184211,

Gene Summary

Adenine Count

1209259 bp

Thymine Count

1207586 bp

Guanine Count

1241547 bp

Cytosine Count

1239791 bp

Genome Length

4898183 bp

Protein-coding Genes

4570 genes

Non-Coding Genes

255 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Dna stabilization proteinE5P20_12555Not AvailableNegative2613947 - 261536552250.8
Dna stabilization proteinE5P20_12560Not AvailableNegative2615375 - 261583616623.7
Hypothetical proteinE5P20_12565Not AvailableNegative2615817 - 26160056960.26
Coat proteinE5P20_12570Not AvailableNegative2616047 - 261730044657.1
Capsid and scaffold proteinE5P20_12575Not AvailableNegative2617293 - 261821334683.4
Portal proteinE5P20_12580Not AvailableNegative2618304 - 262050281704.1
Terminase large subunitE5P20_12585Not AvailableNegative2620504 - 262191953019.1
Hypothetical proteinE5P20_12590Not AvailableNegative2621916 - 262235616760.8
Duf2560 family proteinE5P20_12595Not AvailableNegative2622359 - 26226019012.78
Rha family proteinE5P20_12600Not AvailableNegative2622935 - 262347721100.8

Displaying genes 41 – 50 of 4825 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total