Escherichia coli strain KCJK8392

Escherichia coli strain KCJK8392 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is capable of thriving in pairs or singles and possesses flagella, allowing for mobility. Its optimal growth temperature is 37°C, and it falls within the mesophilic temperature range. Notably, it comprises a single replicon and is characterized by having two membranes. KCJK8392 is associated with various hosts, including Homo sapiens, Gallus gallus (chickens), Bos taurus (cattle), and a wide array of other vertebrates and invertebrates such as Canis lupus familiaris (dogs), Felis catus (cats), and Solanum lycopersicum (tomatoes). This diverse host range indicates its adaptability and potential for interaction with multiple species in different ecological niches. Clinically, E. coli strain KCJK8392 is known for its pathogenicity in humans, being linked to numerous health effects such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia. The strain can cause severe conditions, including hemolytic uremic syndrome (HUS), which is associated with renal failure and gastrointestinal distress. The ability of KCJK8392 to inhabit a wide range of hosts and its significant pathogenic potential underscore its ecological role as both a free-living organism and a pathogen in various environments. This duality reflects the complex interactions E. coli can have in both health and disease contexts, highlighting its importance in microbiological research and public health.