Escherichia coli strain KCJK8357

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8357 is a Gram-negative, rod-shaped bacterium that occurs in pairs or singles and is characterized as a facultative anaerobe. This strain is motile, possessing flagella, and thrives optimally at 37 degrees Celsius, fitting within the mesophilic temperature range. KCJK8357 has a free-living biotic relationship and is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other mammals, birds, and even plants such as Solanum lycopersicum and Brassica oleracea var. italica. The strain is known for its significant health effects in humans, notably causing urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). It has been implicated in various diseases, including peritonitis, diarrhea, and foodborne infections, reflecting its pathogenic potential. With one replicon and two membranes, KCJK8357 exhibits characteristics typical of enteric bacteria. Its ability to thrive in diverse environments and its association with numerous hosts suggest a complex ecological role, particularly in the context of human health and agriculture. The strain's pathogenicity emphasizes the importance of monitoring E. coli in both clinical settings and food safety, given its capacity to cause serious infections and health complications across multiple host species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8357

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8357
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8357

Gene Summary

Adenine Count

1168555 bp

Thymine Count

1162558 bp

Guanine Count

1199099 bp

Cytosine Count

1207583 bp

Genome Length

4737795 bp

Protein-coding Genes

4280 genes

Non-Coding Genes

263 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Ncrna_class:otherNot AvailableNot AvailablePositive74726 - 74857Not Available
nudix hydrolase yfcdE5P16_00340Not AvailableNegative74310 - 7485220376.9
Ncrna_class:otherNot AvailableNot AvailablePositive75023 - 75154Not Available
phosphodiesteraseE5P16_00345Not AvailableNegative74910 - 7546119992.1
glutathione transferaseE5P16_00350Not AvailableNegative75517 - 7616124357.0
gsh-dependent disulfide bond oxidoreductaseE5P16_00355Not AvailablePositive76297 - 7694424517.2
dihydroneopterin triphosphate 2'-epimeraseE5P16_00360Not AvailablePositive77001 - 7736314082.8
tigr01777 family proteinE5P16_00365Not AvailablePositive77384 - 7827732700.7
rpn family recombination-promoting nuclease/putative transposaseE5P16_00370Not AvailableNegative78325 - 7921534181.5
histidine abc transporter atp-binding protein hispE5P16_00375Not AvailableNegative79412 - 8018528654.8

Displaying genes 271 – 280 of 4543 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total