Escherichia coli strain KCJK8229

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8229 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility, facilitated by the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C, and typically arranges itself in pairs or as singles. E. coli KCJK8229 is associated primarily with host organisms, demonstrating a free-living biotic relationship. It has been identified in a wide range of hosts, including mammals such as Homo sapiens, Bos taurus, and Sus scrofa, as well as various other vertebrates and even some plants like Solanum lycopersicum and Brassica oleracea var. italica. This strain is notable for its pathogenic potential in humans, being linked to numerous health issues such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia. Specific health effects attributed to E. coli KCJK8229 include diarrhea, enteric disease, and severe conditions like hemolytic uremic syndrome (HUS) and renal failure. The diversity of infections caused by this strain underscores its significance in clinical microbiology. The broad host range and diverse pathogenic effects of E. coli KCJK8229 highlight its ecological adaptability and the potential for cross-species transmission. This adaptability may contribute to the strain's role in both human health and disease, emphasizing the need for continued surveillance and research into its behavior within different ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8229

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8229
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8229

Gene Summary

Adenine Count

1142833 bp

Thymine Count

1145482 bp

Guanine Count

1185241 bp

Cytosine Count

1188682 bp

Genome Length

4662238 bp

Protein-coding Genes

4308 genes

Non-Coding Genes

145 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rpoe-regulated lipoproteinE5P08_02380Not AvailableNegative481401 - 48197620898.7
duf2919 domain-containing proteinE5P08_02385Not AvailableNegative482037 - 48248617120.3
acetyltransferase ypeaE5P08_02390Not AvailableNegative482473 - 48289816312.5
n-acetylmuramoyl-l-alanine amidase amiaE5P08_02395Not AvailablePositive483112 - 48398131413.9
oxygen-dependent coproporphyrinogen oxidaseE5P08_02400Not AvailablePositive483985 - 48488434324.4
hth-type transcriptional regulator eutrE5P08_02405Not AvailableNegative484890 - 48594240189.1
ethanolamine utilization microcompartment protein eutkE5P08_02410Not AvailableNegative485988 - 48648817893.7
ethanolamine utilization microcompartment protein eutlE5P08_02415Not AvailableNegative486501 - 48716022803.1
ethanolamine ammonia-lyase subunit eutcE5P08_02420Not AvailableNegative487170 - 48805731813.4
ethanolamine ammonia-lyase subunit eutbE5P08_02425Not AvailableNegative488078 - 48943949405.9

Displaying genes 521 – 530 of 4453 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total