Escherichia coli strain KCJK8198

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8198 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, enabling it to thrive in both aerobic and anaerobic environments. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in pairs or singles. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. KCJK8198 is host-associated, demonstrating a diverse range of biotic relationships with numerous hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even plants such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This extensive host range suggests that KCJK8198 may play significant roles in various ecological niches, including both free-living and pathogenic contexts. The strain is linked to numerous health effects, primarily in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The pathogenicity of KCJK8198 appears to be a critical factor in its interactions with host organisms, particularly in causing diseases that affect the urinary and gastrointestinal tracts, which can lead to significant health issues. The ecological insight from the diverse host range and the associated health impacts highlights the importance of monitoring E. coli strains like KCJK8198, as they can serve as indicators of environmental health and food safety, given their potential to cause foodborne illnesses and other infections. Understanding the dynamics of such strains is crucial for public health and disease prevention strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8198

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8198
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8198

Gene Summary

Adenine Count

1135996 bp

Thymine Count

1138525 bp

Guanine Count

1167899 bp

Cytosine Count

1174121 bp

Genome Length

4616541 bp

Protein-coding Genes

4139 genes

Non-Coding Genes

286 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase nadrE5P07_14265Not AvailableNegative2960391 - 296162347323.4
dna repair protein radaE5P07_14270Not AvailableNegative2961644 - 296302649445.0
phosphoserine phosphataseE5P07_14275Not AvailableNegative2963075 - 296404335074.8
ytjb family periplasmic proteinE5P07_14280Not AvailablePositive2964149 - 296479324084.2
lipoate--protein ligase lplaE5P07_14285Not AvailablePositive2964821 - 296583737958.9
xre family transcriptional regulatorE5P07_14290Not AvailablePositive2965869 - 29661329933.28
purine-nucleoside phosphorylaseE5P07_14295Not AvailableNegative2966293 - 296701225937.4
phosphopentomutaseE5P07_14300Not AvailableNegative2967069 - 296829244372.4
thymidine phosphorylaseE5P07_14305Not AvailableNegative2968344 - 296966647182.9
deoxyribose-phosphate aldolaseE5P07_14310Not AvailableNegative2969793 - 297057227749.3

Displaying genes 2921 – 2930 of 4425 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total