Escherichia coli strain KCJK8198

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8198 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, enabling it to thrive in both aerobic and anaerobic environments. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in pairs or singles. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. KCJK8198 is host-associated, demonstrating a diverse range of biotic relationships with numerous hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even plants such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This extensive host range suggests that KCJK8198 may play significant roles in various ecological niches, including both free-living and pathogenic contexts. The strain is linked to numerous health effects, primarily in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The pathogenicity of KCJK8198 appears to be a critical factor in its interactions with host organisms, particularly in causing diseases that affect the urinary and gastrointestinal tracts, which can lead to significant health issues. The ecological insight from the diverse host range and the associated health impacts highlights the importance of monitoring E. coli strains like KCJK8198, as they can serve as indicators of environmental health and food safety, given their potential to cause foodborne illnesses and other infections. Understanding the dynamics of such strains is crucial for public health and disease prevention strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8198

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8198
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8198

Gene Summary

Adenine Count

1135996 bp

Thymine Count

1138525 bp

Guanine Count

1167899 bp

Cytosine Count

1174121 bp

Genome Length

4616541 bp

Protein-coding Genes

4139 genes

Non-Coding Genes

286 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna recombination protein rmucE5P07_13105Not AvailablePositive2734220 - 273564754767.6
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase ubieE5P07_13110Not AvailablePositive2735742 - 273649728074.8
ubiquinone biosynthesis protein ubijE5P07_13115Not AvailablePositive2736511 - 273711622123.8
ubiquinone biosynthesis regulatory protein kinase ubibE5P07_13120Not AvailablePositive2737113 - 273875363234.4
sec-independent protein translocase subunit tataE5P07_13125Not AvailablePositive2738832 - 27391019664.5
sec-independent protein translocase subunit tatbE5P07_13130Not AvailablePositive2739105 - 273962018421.8
sec-independent protein translocase subunit tatcE5P07_13135Not AvailablePositive2739623 - 274039928877.9
3'-5' ssdna/rna exonuclease tatdE5P07_13140Not AvailablePositive2740441 - 274122329027.6
transcription/translation regulatory transformer protein rfahE5P07_13145Not AvailableNegative2741220 - 274170818341.3
4-hydroxy-3-polyprenylbenzoate decarboxylaseE5P07_13150Not AvailablePositive2741875 - 274336855606.8

Displaying genes 2691 – 2700 of 4425 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total