Escherichia coli strain KCJK8192

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8192 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. This strain typically exists in pairs or as single cells and possesses flagella, which contribute to its mobility. The optimal growth temperature for KCJK8192 is 37°C, characteristic of mesophilic organisms. The strain is host-associated and demonstrates a free-living biotic relationship, with a diverse range of hosts that includes Homo sapiens, various livestock such as Bos taurus (cattle) and Gallus gallus (chickens), as well as numerous other vertebrates and invertebrates like Sus scrofa (pigs) and Apis mellifera (honeybees). KCJK8192 is notable for its significant health impacts on humans, being associated with a wide array of infections and diseases. These include urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain is also implicated in foodborne illnesses, which underscores its role in public health concerns. Given its pathogenicity in humans and association with various hosts, Escherichia coli strain KCJK8192 exemplifies the complex interplay between microbial organisms and their environments. Its widespread presence across diverse species highlights the importance of understanding such pathogens in the context of zoonotic diseases and food safety, emphasizing the need for continued vigilance in monitoring and controlling infections associated with this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8192

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8192
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8192 NODE_78_length_225_cov_44.275510,

Gene Summary

Adenine Count

1138233 bp

Thymine Count

1139470 bp

Guanine Count

1186435 bp

Cytosine Count

1156071 bp

Genome Length

4620209 bp

Protein-coding Genes

4114 genes

Non-Coding Genes

317 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
propanediol dehydrataseE5P03_18145Not AvailableNegative3785249 - 378559912979.7
diol dehydratase reactivase subunit alphaE5P03_18150Not AvailableNegative3785589 - 378742164384.2
propanediol dehydratase small subunit pdueE5P03_18155Not AvailableNegative3787431 - 378794919356.9
propanediol/glycerol family dehydratase medium subunitE5P03_18160Not AvailableNegative3787964 - 378863224153.2
propanediol dehydratase large subunit pducE5P03_18165Not AvailableNegative3788642 - 379030660462.9
propanediol utilization microcompartment protein pdubE5P03_18170Not AvailableNegative3790325 - 379113728202.8
propanediol utilization microcompartment protein pduaE5P03_18175Not AvailableNegative3791134 - 37914189570.74
propanediol diffusion facilitator pdufE5P03_18180Not AvailablePositive3791930 - 379273928066.8
regulatory protein pocrE5P03_18185Not AvailablePositive3792942 - 379385634658.5
cobalamin biosynthesis proteinE5P03_18190Not AvailablePositive3794341 - 379477815672.7

Displaying genes 3711 – 3720 of 4431 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total