Escherichia coli strain KCJK8170

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8170 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is typically found in host-associated environments, indicating a strong relationship with various hosts, including Homo sapiens, Gallus gallus, and Bos taurus, among others. The optimal temperature for KCJK8170 is 37°C, making it mesophilic and well-suited for growth in warm-blooded hosts. Its biotic relationship is characterized as free-living, allowing it to thrive in diverse biological contexts. KCJK8170 has a singular replicon and contains two membranes, which is characteristic of Gram-negative bacteria. This strain is associated with a wide array of health effects, particularly in humans, where it can lead to conditions such as urinary tract infections (UTIs), gastrointestinal infections, and more severe complications like neonatal meningitis and hemolytic uremic syndrome (HUS). The bacterium's pathogenicity is notably linked to various clinical manifestations, including foodborne illnesses and diarrheal diseases, underscoring its role as a significant public health concern. The diverse range of hosts suggests that KCJK8170 may have an ecological niche that allows it to adapt and persist in various environments, including those associated with both animals and plants. This adaptability highlights the importance of monitoring such strains in zoonotic disease transmission and food safety, given the potential for serious health impacts associated with its pathogenicity.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8170

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8170
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8170

Gene Summary

Adenine Count

1167646 bp

Thymine Count

1172544 bp

Guanine Count

1209613 bp

Cytosine Count

1213072 bp

Genome Length

4762875 bp

Protein-coding Genes

4322 genes

Non-Coding Genes

321 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
smdb family multidrug efflux abc transporter permease/atp-binding proteinE5P02_08010Not AvailableNegative1651084 - 165286565295.6
smda family multidrug abc transporter permease/atp-binding proteinE5P02_08015Not AvailableNegative1652858 - 165463065975.3
lrp/asnc family transcriptional regulatorE5P02_08020Not AvailableNegative1654660 - 165511817438.4
hmp-pp phosphataseE5P02_08025Not AvailableNegative1655271 - 165608930346.7
sgrr family transcriptional regulatorE5P02_08030Not AvailablePositive1656189 - 165788964996.2
7-cyano-7-deazaguanine synthase quecE5P02_08035Not AvailablePositive1657954 - 165864925511.6
ybgc/fadm family acyl-coa thioesteraseE5P02_08040Not AvailableNegative1658701 - 165909915089.2
hypothetical proteinE5P02_08045Not AvailableNegative1659205 - 165957612760.5
peptidylprolyl isomeraseE5P02_08050Not AvailableNegative1659727 - 166159868165.8
dna-binding protein hu-betaE5P02_08055Not AvailableNegative1661790 - 16620629226.08

Displaying genes 1801 – 1810 of 4643 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total