Escherichia coli strain KCJK8160

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8160 is a Gram-negative, rod-shaped bacterium that exhibits motility, characterized by the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, situating it within the mesophilic range. KCJK8160 is notably host-associated, engaging in free-living biotic relationships with a wide array of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as diverse species like Gallus gallus, Oryctolagus cuniculus, and even insects like Apis mellifera. This broad host range highlights the organism's ecological versatility and adaptability. The health implications of KCJK8160 are significant, as it is associated with numerous conditions, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. These health effects can lead to severe outcomes such as hemolytic uremic syndrome (HUS) and septicemia. The strain's pathogenicity is primarily noted in humans, marking it as a notable concern in clinical microbiology. The presence of a single replicon and a double membrane structure aligns with typical E. coli characteristics, emphasizing its classification within the Enterobacteriaceae family. The strain’s ability to cause various infections reinforces the importance of understanding its ecological role and potential impact on health, particularly in environments where humans and domestic animals interact closely.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8160

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8160
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8160 NODE_59_length_231_cov_12.048077,

Gene Summary

Adenine Count

1202233 bp

Thymine Count

1205980 bp

Guanine Count

1248745 bp

Cytosine Count

1229318 bp

Genome Length

4886276 bp

Protein-coding Genes

4266 genes

Non-Coding Genes

388 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-asnNot AvailableNot AvailablePositive4532258 - 4532333Not Available
dgsa anti-repressor mtfaE5P01_21765Not AvailableNegative4532434 - 453323130280.7
Trna-serNot AvailableNot AvailablePositive4533325 - 4533414Not Available
cytochrome bE5P01_21775Not AvailableNegative4533984 - 453451420338.4
metal-binding protein zintE5P01_21780Not AvailableNegative4534857 - 453552825523.0
protein-methionine-sulfoxide reductase heme-binding subunit msrqE5P01_21785Not AvailableNegative4535764 - 453639924069.6
protein-methionine-sulfoxide reductase catalytic subunit msrpE5P01_21790Not AvailableNegative4536400 - 453740437366.9
hydroxyisourate hydrolaseE5P01_21795Not AvailableNegative4537513 - 453792615537.6
dna-binding response regulator hprrE5P01_21800Not AvailablePositive4538059 - 453873025010.2
heavy metal sensor histidine kinaseE5P01_21805Not AvailablePositive4538730 - 454008850790.6

Displaying genes 4331 – 4340 of 4654 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total