Escherichia coli strain KCJK8160

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8160 is a Gram-negative, rod-shaped bacterium that exhibits motility, characterized by the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. Its optimal growth temperature is 37°C, situating it within the mesophilic range. KCJK8160 is notably host-associated, engaging in free-living biotic relationships with a wide array of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as diverse species like Gallus gallus, Oryctolagus cuniculus, and even insects like Apis mellifera. This broad host range highlights the organism's ecological versatility and adaptability. The health implications of KCJK8160 are significant, as it is associated with numerous conditions, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis, among others. These health effects can lead to severe outcomes such as hemolytic uremic syndrome (HUS) and septicemia. The strain's pathogenicity is primarily noted in humans, marking it as a notable concern in clinical microbiology. The presence of a single replicon and a double membrane structure aligns with typical E. coli characteristics, emphasizing its classification within the Enterobacteriaceae family. The strain’s ability to cause various infections reinforces the importance of understanding its ecological role and potential impact on health, particularly in environments where humans and domestic animals interact closely.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8160

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8160
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8160 NODE_59_length_231_cov_12.048077,

Gene Summary

Adenine Count

1202233 bp

Thymine Count

1205980 bp

Guanine Count

1248745 bp

Cytosine Count

1229318 bp

Genome Length

4886276 bp

Protein-coding Genes

4266 genes

Non-Coding Genes

388 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dipeptide abc transporter atp-binding proteinE5P01_15415Not AvailablePositive3185730 - 318671335846.5
dipeptide abc transporter atp binding subunit dppfE5P01_15420Not AvailablePositive3186710 - 318771437520.6
transporterE5P01_15425Not AvailableNegative3187744 - 318901547301.3
type i toxin-antitoxin system toxin ldr family proteinE5P01_15430Not AvailablePositive3189492 - 31895993882.93
type i toxin-antitoxin system toxin ldr family proteinE5P01_15435Not AvailablePositive3189975 - 31900823882.93
type i toxin-antitoxin system toxin ldr family proteinE5P01_15445Not AvailablePositive3190458 - 31905653882.93
cellulose biosynthesis protein bcsgE5P01_15450Not AvailableNegative3190652 - 319233162047.4
cellulose biosynthesis protein bcsfE5P01_15455Not AvailableNegative3192328 - 31925197364.39
cellulose biosynthesis protein bcseE5P01_15460Not AvailableNegative3192516 - 319408759415.5
hypothetical proteinE5P01_15465Not AvailablePositive3194360 - 31945487032.31

Displaying genes 3081 – 3090 of 4654 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total