Escherichia coli strain KCJK8128

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8128 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C. E. coli KCJK8128 is characterized by its habitat as being host-associated, and it displays a free-living biotic relationship. The strain has been associated with a variety of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, and other animals including Canis lupus familiaris and Felis catus. Additionally, it can interact with various plants and invertebrates, indicating a broad ecological range. E. coli KCJK8128 is linked to numerous health effects, notably urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). It can also lead to complications like septicemia, renal failure, and even colorectal cancer. The extensive list of diseases associated with this strain underscores its pathogenic potential in both humans and animals. Understanding the traits and pathogenicity of E. coli strain KCJK8128 is crucial for addressing public health concerns, especially given its role in various infections and the potential for foodborne diseases. The strain's ability to thrive in diverse environments and hosts highlights the importance of monitoring and researching E. coli as a significant pathogen in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8128

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8128
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8128

Gene Summary

Adenine Count

1199545 bp

Thymine Count

1207172 bp

Guanine Count

1243212 bp

Cytosine Count

1247816 bp

Genome Length

4897745 bp

Protein-coding Genes

4564 genes

Non-Coding Genes

221 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
class 1b ribonucleoside-diphosphate reductase subunit alphaE5P00_23190Not AvailablePositive4656207 - 465835180453.5
ribonucleoside-diphosphate reductase 2 subunit betaE5P00_23195Not AvailablePositive4658361 - 465932036445.1
glycine betaine/l-proline abc transporter atp-binding proteinE5P00_23200Not AvailablePositive4659470 - 46596738026.56
aromatic amino acid dmt transporter yddgE5P00_23205Not AvailableNegative4659799 - 466068031560.4
sulfate abc transporter substrate-binding proteinE5P00_23210Not AvailablePositive4660912 - 466149921465.8
formate dehydrogenase-n subunit alphaE5P00_23215Not AvailablePositive4661548 - 466395989884.8
formate dehydrogenase subunit betaE5P00_23220Not AvailablePositive4663972 - 466485632240.4
formate dehydrogenase-n subunit gammaE5P00_23225Not AvailablePositive4664849 - 466550225370.0
rhs repeat proteinE5P00_23230Not AvailableNegative4665701 - 466841699805.7
type vi secretion system tip protein vgrgE5P00_23235Not AvailableNegative4668483 - 467059178797.0

Displaying genes 4481 – 4490 of 4785 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total