Escherichia coli strain KCJK8128

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8128 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C. E. coli KCJK8128 is characterized by its habitat as being host-associated, and it displays a free-living biotic relationship. The strain has been associated with a variety of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, and other animals including Canis lupus familiaris and Felis catus. Additionally, it can interact with various plants and invertebrates, indicating a broad ecological range. E. coli KCJK8128 is linked to numerous health effects, notably urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). It can also lead to complications like septicemia, renal failure, and even colorectal cancer. The extensive list of diseases associated with this strain underscores its pathogenic potential in both humans and animals. Understanding the traits and pathogenicity of E. coli strain KCJK8128 is crucial for addressing public health concerns, especially given its role in various infections and the potential for foodborne diseases. The strain's ability to thrive in diverse environments and hosts highlights the importance of monitoring and researching E. coli as a significant pathogen in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8128

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8128
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8128

Gene Summary

Adenine Count

1199545 bp

Thymine Count

1207172 bp

Guanine Count

1243212 bp

Cytosine Count

1247816 bp

Genome Length

4897745 bp

Protein-coding Genes

4564 genes

Non-Coding Genes

221 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
methylglyoxal reductase yeaeE5P00_05045Not AvailablePositive1061509 - 106236331018.4
d-hexose-6-phosphate mutarotaseE5P00_05050Not AvailableNegative1062411 - 106329532733.0
glyceraldehyde-3-phosphate dehydrogenaseE5P00_05055Not AvailableNegative1063379 - 106437435534.5
peptide-methionine (r)-s-oxide reductaseE5P00_05060Not AvailablePositive1064716 - 106512915452.0
duf1315 family proteinE5P00_05065Not AvailablePositive1065171 - 106544310338.6
zinc-binding dehydrogenaseE5P00_05070Not AvailablePositive1065813 - 106611210577.7
alcohol dehydrogenaseE5P00_05075Not AvailablePositive1066122 - 106688927744.8
mfs transporterE5P00_05080Not AvailablePositive1066916 - 106829549590.9
nad(p)-dependent alcohol dehydrogenaseE5P00_05085Not AvailablePositive1068312 - 106935537821.2
ketose-bisphosphate aldolaseE5P00_05090Not AvailablePositive1069376 - 107021230821.5

Displaying genes 1131 – 1140 of 4785 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total