Escherichia coli strain KCJK8124

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8124 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, which allows it to thrive in various oxygen conditions. Its habitat is primarily host-associated, indicating a close relationship with a range of hosts, including Homo sapiens, Gallus gallus, and various other vertebrates, invertebrates, and plants. The strain is motile, possessing flagella, and is mesophilic, with an optimal growth temperature of 37°C. It features a typical double-membrane structure and contains a single replicon, which is characteristic of many E. coli strains. KCJK8124 is known for its pathogenicity in humans, associated with a variety of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain has also been implicated in foodborne infections, gastrointestinal diseases, and complications such as renal failure and septicemia. The wide array of hosts and the significant health effects linked to KCJK8124 highlight its ecological role as a free-living organism that can impact a variety of biological systems. Its presence in both human and animal populations suggests that understanding this strain is crucial for public health, particularly in the context of preventing and managing infections caused by this versatile pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8124

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8124
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8124

Gene Summary

Adenine Count

1137030 bp

Thymine Count

1138376 bp

Guanine Count

1175525 bp

Cytosine Count

1177288 bp

Genome Length

4628219 bp

Protein-coding Genes

4305 genes

Non-Coding Genes

153 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hila family transcriptional regulator ygehE5O99_22335Not AvailablePositive4556954 - 455761825480.6
lipopolysaccharide 3-alpha-galactosyltransferaseE5O99_22340Not AvailablePositive4557619 - 455856836525.9
lipopolysaccharide glucosyltransferase rfajE5O99_22345Not AvailablePositive4558608 - 455956737070.8
3-deoxy-d-manno-oct-2-ulosonate iii transferase waazE5O99_22350Not AvailablePositive4559568 - 456035130226.5
lipopolysaccharide heptosyltransferase family proteinE5O99_22355Not AvailablePositive4560384 - 456144641369.2
acetyltransferaseE5O99_22365Not AvailableNegative4561676 - 456211916577.7
homoserine o-succinyltransferaseE5O99_22370Not AvailablePositive4562276 - 456320535715.1
type iii effector proteinE5O99_22375Not AvailablePositive4563319 - 456370515222.1
hypothetical proteinE5O99_22380Not AvailableNegative4564177 - 456452713306.9
porin ompcE5O99_22390Not AvailablePositive4565116 - 456620440469.6

Displaying genes 4341 – 4350 of 4458 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total