Escherichia coli strain KCJK8124

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8124 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, which allows it to thrive in various oxygen conditions. Its habitat is primarily host-associated, indicating a close relationship with a range of hosts, including Homo sapiens, Gallus gallus, and various other vertebrates, invertebrates, and plants. The strain is motile, possessing flagella, and is mesophilic, with an optimal growth temperature of 37°C. It features a typical double-membrane structure and contains a single replicon, which is characteristic of many E. coli strains. KCJK8124 is known for its pathogenicity in humans, associated with a variety of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain has also been implicated in foodborne infections, gastrointestinal diseases, and complications such as renal failure and septicemia. The wide array of hosts and the significant health effects linked to KCJK8124 highlight its ecological role as a free-living organism that can impact a variety of biological systems. Its presence in both human and animal populations suggests that understanding this strain is crucial for public health, particularly in the context of preventing and managing infections caused by this versatile pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8124

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8124
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8124

Gene Summary

Adenine Count

1137030 bp

Thymine Count

1138376 bp

Guanine Count

1175525 bp

Cytosine Count

1177288 bp

Genome Length

4628219 bp

Protein-coding Genes

4305 genes

Non-Coding Genes

153 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fe-s protein assembly chaperone hscaE5O99_08830Not AvailablePositive1833230 - 183508065584.2
isc system 2fe-2s type ferredoxinE5O99_08835Not AvailablePositive1835082 - 183541712331.5
fe-s cluster assembly protein iscxE5O99_08840Not AvailablePositive1835429 - 18356297731.92
aminopeptidase pepbE5O99_08845Not AvailablePositive1835688 - 183697146237.7
enhanced serine sensitivity protein ssebE5O99_08850Not AvailablePositive1837114 - 183789028628.1
3-mercaptopyruvate sulfurtransferaseE5O99_08855Not AvailableNegative1838387 - 183923230817.5
alpha2-macroglobulinE5O99_08860Not AvailablePositive1839439 - 1844400181667.0
peptidoglycan glycosyltransferase pbpcE5O99_08865Not AvailablePositive1844401 - 184671385078.7
pentapeptide repeat-containing proteinE5O99_08870Not AvailableNegative1846772 - 184799046769.1
hypothetical proteinE5O99_08875Not AvailablePositive1848410 - 18485926639.99

Displaying genes 1821 – 1830 of 4458 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total