Escherichia coli strain KCJK8065

Escherichia coli strain KCJK8065 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It typically resides in host-associated habitats, primarily affecting a wide range of hosts, including Homo sapiens, various livestock (such as Bos taurus and Gallus gallus), and numerous other mammals, birds, and even some plants. KCJK8065 is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the body temperature of humans and many warm-blooded animals. The strain possesses a single replicon and is characterized by having two membranes, a trait common to Gram-negative bacteria. This strain is notably pathogenic to humans, associated with a variety of health effects, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. The diverse list of health effects indicates that KCJK8065 can cause significant morbidity, affecting not only the urinary tract but also leading to complications such as neonatal meningitis and colibacillosis. Ecologically, the ability of KCJK8065 to inhabit multiple hosts highlights its versatility and adaptability. Its pathogenic nature, combined with its presence in both human and animal hosts, underscores the importance of monitoring and understanding such strains in the context of public health, particularly regarding zoonotic transmission and foodborne infections.