Salmonella enterica subsp. enterica serovar Typhi strain 15604

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Salmonella

Description

Salmonella enterica subsp. enterica serovar Typhi strain 15604 is a Gram-negative bacterium that exhibits a microaerophilic oxygen requirement and possesses flagella. Its cellular arrangement is characterized by chains and singles, and it takes on a spirilla shape. Strain 15604 is a chemoorganotroph, deriving its energy from organic compounds, and it thrives optimally at a temperature of 37°C, falling within the mesophilic temperature range. This strain has a unique biotic relationship, being free-living, but it is also host-associated, primarily infecting Homo sapiens and Pteropodidae. It is known to cause significant health issues, including acute cholecystitis, bloodstream infections, typhoid fever, and enteric fever. The presence of a single replicon and two membranes aligns with its classification within the Salmonella genus, which is known for its pathogenic capabilities. The ecological role of Salmonella enterica serovar Typhi strain 15604 highlights its adaptation to specific hosts and environments. Its pathogenicity in humans underscores the importance of understanding its lifecycle and transmission dynamics, particularly in relation to public health. The bacterium's ability to cause severe illnesses emphasizes the need for continued research and monitoring to mitigate its impact on affected populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusSalmonella
SpeciesSalmonella enterica
Strainsubsp. enterica serovar Typhi strain 15604

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Salmonella enterica subsp. enterica serovar Typhi strain 15604
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Pteropodidae
Cell arrangementChains - Singles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Salmonella enterica subsp. enterica serovar Typhi strain 15604

Gene Summary

Adenine Count

1171408 bp

Thymine Count

1158061 bp

Guanine Count

1250284 bp

Cytosine Count

1276170 bp

Genome Length

4855923 bp

Protein-coding Genes

4275 genes

Non-Coding Genes

453 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional trna pseudouridine(32) synthase/23s rrna pseudouridine(746) synthase rluaE3D93_24830Not AvailablePositive4812829 - 481348824771.0
co-chaperone djlaE3D93_24835Not AvailableNegative4813583 - 481439530585.2
lps assembly protein lptdE3D93_24840Not AvailablePositive4814649 - 481700389649.1
peptidylprolyl isomerase suraE3D93_24845Not AvailablePositive4817057 - 481834347253.6
4-hydroxythreonine-4-phosphate dehydrogenase pdxaE3D93_24850Not AvailablePositive4818343 - 481933234827.6
16s rrna (adenine(1518)-n(6)/adenine(1519)-n(6))- dimethyltransferase rsmaE3D93_24855Not AvailablePositive4819329 - 482015030518.1
co2+/mg2+ efflux protein apagE3D93_24860Not AvailablePositive4820153 - 482053013893.6
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)E3D93_24865Not AvailablePositive4820541 - 482138931432.4
type 3 dihydrofolate reductaseE3D93_24870Not AvailableNegative4821485 - 482196417985.3
glutathione-regulated potassium-efflux system protein kefcE3D93_24875Not AvailableNegative4822163 - 482402567036.0

Displaying genes 4691 – 4700 of 4728 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Acute cholecystitisCausesPMC10442058
Typhoid feverCausesPMC7845599
Typhoid feverCausesPMC10178548
Enteric feverCausesPMC10178548
Bloodstream infectionsCausesPMC10178548
TyphoidCausesPMC9967847

Displaying health effects 1 – 6 of 6 in total