Klebsiella pneumoniae strain NUBRI-K 137

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain NUBRI-K 137 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism. This strain is classified as a chemoheterotroph, deriving energy from organic compounds, and is capable of existing in various cell arrangements, including chains, pairs, and singles. It is motile and possesses flagella, allowing for movement within its host-associated habitat. Optimal growth for NUBRI-K 137 occurs at 37°C, indicating its mesophilic nature. The bacterium has one replicon and two membranes, a typical feature of Gram-negative organisms. It exhibits a free-living biotic relationship and has a broad host range, affecting various species including humans (Homo sapiens), chickens (Gallus gallus), and other vertebrates such as zebrafish (Danio rerio) and domestic animals like dogs (Canis lupus familiaris) and pigs (Sus scrofa). Klebsiella pneumoniae is known for its pathogenicity in humans, causing a wide array of health issues. These include bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The bacterium's ability to cause such diverse infections highlights its adaptability and potential for opportunistic pathogenicity in various environments. Ecologically, the presence of K. pneumoniae in diverse hosts suggests its role in microbial communities associated with both humans and animals. Its pathogenic potential, coupled with its ability to thrive in multiple hosts, underscores the importance of monitoring this strain in clinical and environmental contexts to understand its impact on health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain NUBRI-K 137

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain NUBRI-K 137
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain NUBRI-K 137, whole genome shotgun

Gene Summary

Adenine Count

1279910 bp

Thymine Count

1270678 bp

Guanine Count

1653799 bp

Cytosine Count

1676109 bp

Genome Length

5880496 bp

Protein-coding Genes

5528 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
OxidoreductaseE1753_13820Not AvailablePositive2826455 - 282818265401.3
Portal proteinE1753_13825Not AvailablePositive2828176 - 282923739406.3
duf4435 domain-containing proteinE1753_13830Not AvailableNegative2829844 - 283070433219.3
aaa family atpaseE1753_13835Not AvailableNegative2830701 - 283194847650.9
Replication endonucleaseE1753_13840Not AvailableNegative2832132 - 283415977076.7
Dna adenine methylaseE1753_13845Not AvailableNegative2834197 - 283513235152.8
Hypothetical proteinE1753_13850Not AvailableNegative2835129 - 28353568761.86
3'-5' exoribonucleaseE1753_13855Not AvailableNegative2835365 - 283593121041.1
Hypothetical proteinE1753_13860Not AvailableNegative2835928 - 28361528208.83
Hypothetical proteinE1753_13865Not AvailableNegative2836230 - 283649310453.6

Displaying genes 121 – 130 of 5834 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total