Escherichia coli strain EC_11

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain EC_11 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain exhibits mobility, attributed to the presence of flagella, and typically exists in pairs or singles. It is free-living but has a significant host-associated habitat, being found in various organisms including Homo sapiens, Gallus gallus, and Bos taurus, among others, indicating a broad ecological niche. EC_11 is known for its pathogenicity in humans, linked to a variety of health issues. The strain is notably associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). Other health effects include peritonitis, diarrhea, and complications that may lead to renal failure or even abortion. The extensive list of diseases underscores the strain's potential impact on human health and highlights its role as a significant public health concern. Given its diverse range of hosts and the extensive array of health effects, E. coli strain EC_11 serves as a crucial example of how environmental and biological interactions can influence pathogenicity. Its presence in both human and animal hosts emphasizes the interconnectedness of ecosystems and the importance of monitoring such strains in the context of public health and disease prevention.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain EC_11

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain EC_11
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain EC_11 NODE_142_length_527_cov_25.628889,

Gene Summary

Adenine Count

1403876 bp

Thymine Count

1403803 bp

Guanine Count

1425476 bp

Cytosine Count

1394297 bp

Genome Length

5627615 bp

Protein-coding Genes

5194 genes

Non-Coding Genes

281 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive1393628 - 1393640Not Available
AttlNot AvailableNot AvailablePositive1401973 - 1401984Not Available
Hypothetical proteinEXX13_06505Not AvailableNegative1407144 - 14072995941.19
Dna primaseEXX13_06510Not AvailableNegative1407503 - 140983684832.2
Hypothetical proteinEXX13_06515Not AvailableNegative1409851 - 141017111802.6
Hypothetical proteinEXX13_06520Not AvailableNegative1410307 - 141076217783.2
Helper derepression proteinEXX13_06525Not AvailableNegative1410755 - 141104210937.0
Putative ci repressorEXX13_06530Not AvailableNegative1411035 - 141163421408.0
Transcriptional regulatorEXX13_06535Not AvailableNegative1411631 - 14118979763.97
hypotheticalEXX13_06540Not AvailableNegative1411910 - 14121016776.18

Displaying genes 1 – 10 of 5475 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Renal failureCausesPMC3505186
MeningitisCausesPMC3505186
Urinary tract infectionsCausesPMC3789825
Bloodstream infectionsCausesPMC3789825
Acute pyelonephritisCausesPMC3789825
OsteomyelitisCausesPMC3789825
Septic arthritisCausesPMC3789825
Septic shockCausesPMC3789825
Invasive diseaseCausesPMC3789825
UtiCausesPMC3789825

Displaying health effects 91 – 100 of 103 in total