Escherichia coli strain EC_11

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain EC_11 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain exhibits mobility, attributed to the presence of flagella, and typically exists in pairs or singles. It is free-living but has a significant host-associated habitat, being found in various organisms including Homo sapiens, Gallus gallus, and Bos taurus, among others, indicating a broad ecological niche. EC_11 is known for its pathogenicity in humans, linked to a variety of health issues. The strain is notably associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). Other health effects include peritonitis, diarrhea, and complications that may lead to renal failure or even abortion. The extensive list of diseases underscores the strain's potential impact on human health and highlights its role as a significant public health concern. Given its diverse range of hosts and the extensive array of health effects, E. coli strain EC_11 serves as a crucial example of how environmental and biological interactions can influence pathogenicity. Its presence in both human and animal hosts emphasizes the interconnectedness of ecosystems and the importance of monitoring such strains in the context of public health and disease prevention.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain EC_11

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain EC_11
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain EC_11


Gene Summary

Adenine Count

1403876 bp

Thymine Count

1403803 bp

Guanine Count

1425476 bp

Cytosine Count

1394297 bp

Genome Length

5627615 bp

Protein-coding Genes

5194 genes

Non-Coding Genes

281 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
serine dehydratase subunit alpha family proteinEXX13_07530Not AvailablePositive1604177 - 160548745317.8
hypothetical proteinEXX13_07535Not AvailableNegative1605620 - 16057845949.06
pirin family proteinEXX13_07540Not AvailableNegative1605807 - 160650825897.0
lysr family transcriptional regulatorEXX13_07545Not AvailablePositive1606613 - 160750933258.3
duf805 domain-containing proteinEXX13_07555Not AvailableNegative1608165 - 160853014281.7
glutathione s-transferase family proteinEXX13_07560Not AvailableNegative1608823 - 160980937502.1
doxx family proteinEXX13_07565Not AvailableNegative1609879 - 161036117216.6
hypothetical proteinEXX13_07570Not AvailableNegative1610457 - 161075611781.4
hypothetical proteinEXX13_07575Not AvailableNegative1610746 - 161115015148.0
duf883 domain-containing proteinEXX13_07580Not AvailableNegative1611153 - 161145811052.1

Displaying genes 1691 – 1700 of 5475 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

945 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da

Displaying 1–10 of 945 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total