Escherichia coli strain EC_25

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain EC_25 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain exhibits mobility, characterized by the presence of flagella, and typically exists in pairs or singles. It has a biotic relationship as a free-living organism and possesses one replicon and two membranes. EC_25 is notably associated with a wide variety of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. This extensive host range indicates its adaptability and ecological versatility. The strain is implicated in numerous health effects, primarily related to urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). Its role in foodborne infections and diseases such as colibacillosis and septicemia highlights its pathogenic potential, particularly in humans. The presence of EC_25 in diverse animal species, including livestock and domestic animals, raises important considerations regarding zoonotic transmission and public health. Its ability to cause a variety of infections underscores the need for ongoing surveillance and research to understand its ecological impact and persistence in various environments. The strain's association with serious health conditions, including renal failure and gastrointestinal diseases, further emphasizes the importance of monitoring E. coli strains in both clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain EC_25

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain EC_25
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain EC_25 NODE_144_length_501_cov_11.787736,

Gene Summary

Adenine Count

1317644 bp

Thymine Count

1318563 bp

Guanine Count

1359669 bp

Cytosine Count

1319404 bp

Genome Length

5315401 bp

Protein-coding Genes

4795 genes

Non-Coding Genes

303 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Signal recognition particle proteinEXX23_13515Not AvailableNegative2872543 - 287390449790.5
Inner membrane protein ypjdEXX23_13520Not AvailablePositive2874071 - 287486229277.9
Hlyc/corc family transporterEXX23_13525Not AvailablePositive2874884 - 287617048047.2
Heat shock proteinEXX23_13530Not AvailableNegative2876225 - 287681821813.1
molecular chaperone grpeEXX23_13535Not AvailableNegative2876815 - 28770097202.78
Dna repair protein recnEXX23_13540Not AvailablePositive2876941 - 287781932568.3
Dna repair protein recnEXX23_13545Not AvailablePositive2877905 - 287956661401.1
Outer membrane protein assembly factor bameEXX23_13550Not AvailablePositive2879715 - 288005612302.8
Rnfh family proteinEXX23_13555Not AvailableNegative2880118 - 288040810790.0
Type ii toxin-antitoxin system toxin rataEXX23_13560Not AvailableNegative2880398 - 288087417743.7

Displaying genes 31 – 40 of 5098 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total