Escherichia coli strain EC_26

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain EC_26 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. It exhibits mobility due to the presence of flagella and typically occurs in pairs or as singles. This strain is host-associated and demonstrates a free-living biotic relationship, with a wide range of hosts including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals, birds, and even plants. EC_26 is known for its significant health effects in humans, being implicated in numerous conditions such as urinary tract infections (UTIs), gastrointestinal infections, peritonitis, and several forms of meningitis. It is also associated with severe outcomes such as hemolytic uremic syndrome (HUS) and renal failure. The strain contributes to a variety of enteric diseases and foodborne infections, indicating its potential for causing outbreaks of gastrointestinal distress. The presence of this strain in multiple host species, including livestock and domesticated animals, raises ecological concerns regarding zoonotic transmission and the potential for food contamination. Its pathogenicity in humans suggests a critical role in public health, particularly in relation to food safety and hygiene practices. Understanding the host interactions and pathogenic mechanisms of EC_26 is essential for developing strategies to manage infections and mitigate associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain EC_26

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain EC_26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain EC_26 NODE_125_length_505_cov_24.742991,

Gene Summary

Adenine Count

1316168 bp

Thymine Count

1319855 bp

Guanine Count

1338011 bp

Cytosine Count

1340572 bp

Genome Length

5324493 bp

Protein-coding Genes

4757 genes

Non-Coding Genes

444 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenaseEXX24_12725Not AvailablePositive2689074 - 268988628471.3
phenylpropionate dioxygenase ferredoxin reductase subunitEXX24_12730Not AvailablePositive2689896 - 269109843966.8
doxx family proteinEXX24_12735Not AvailablePositive2691195 - 269161715212.3
aldose 1-epimeraseEXX24_12740Not AvailableNegative2691665 - 269253732587.0
alcohol dehydrogenaseEXX24_12745Not AvailableNegative2692549 - 269361038066.2
abc transporter permeaseEXX24_12750Not AvailableNegative2693676 - 269467434499.7
sugar abc transporter atp-binding proteinEXX24_12755Not AvailableNegative2694699 - 269621055067.9
sugar abc transporter substrate-binding proteinEXX24_12760Not AvailableNegative2696233 - 269721635073.2
duf5107 domain-containing proteinEXX24_12765Not AvailableNegative2697313 - 2700594123886.0
rok family proteinEXX24_12770Not AvailablePositive2700712 - 270190544569.3

Displaying genes 2841 – 2850 of 5204 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total