Escherichia coli strain EC_26

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain EC_26 is a Gram-negative, rod-shaped bacterium that is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. It exhibits mobility due to the presence of flagella and typically occurs in pairs or as singles. This strain is host-associated and demonstrates a free-living biotic relationship, with a wide range of hosts including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals, birds, and even plants. EC_26 is known for its significant health effects in humans, being implicated in numerous conditions such as urinary tract infections (UTIs), gastrointestinal infections, peritonitis, and several forms of meningitis. It is also associated with severe outcomes such as hemolytic uremic syndrome (HUS) and renal failure. The strain contributes to a variety of enteric diseases and foodborne infections, indicating its potential for causing outbreaks of gastrointestinal distress. The presence of this strain in multiple host species, including livestock and domesticated animals, raises ecological concerns regarding zoonotic transmission and the potential for food contamination. Its pathogenicity in humans suggests a critical role in public health, particularly in relation to food safety and hygiene practices. Understanding the host interactions and pathogenic mechanisms of EC_26 is essential for developing strategies to manage infections and mitigate associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain EC_26

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain EC_26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain EC_26 NODE_125_length_505_cov_24.742991,

Gene Summary

Adenine Count

1316168 bp

Thymine Count

1319855 bp

Guanine Count

1338011 bp

Cytosine Count

1340572 bp

Genome Length

5324493 bp

Protein-coding Genes

4757 genes

Non-Coding Genes

444 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
leucyl/phenylalanyl-trna--protein transferaseEXX24_07665Not AvailablePositive1642144 - 164284826620.0
translation initiation factor if-1EXX24_07670Not AvailablePositive1643133 - 16433518250.1
Trna-serNot AvailableNot AvailablePositive1643605 - 1643692Not Available
atp-dependent clp protease atp-binding subunit clpaEXX24_07685Not AvailableNegative1644036 - 164631284229.9
atp-dependent clp protease adapter clpsEXX24_07690Not AvailableNegative1646343 - 164666312179.7
cold shock-like protein cspdEXX24_07695Not AvailablePositive1646986 - 16472107969.41
macrolide abc transporter atp-binding protein/permease macbEXX24_07700Not AvailableNegative1647283 - 164922970590.7
maca family efflux pump subunitEXX24_07705Not AvailableNegative1649226 - 165034140656.4
duf535 domain-containing proteinEXX24_07710Not AvailablePositive1650492 - 165144836951.0
atp-dependent endonucleaseEXX24_07715Not AvailableNegative1651445 - 165310363560.9

Displaying genes 1881 – 1890 of 5204 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total