Klebsiella pneumoniae strain 53

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain 53 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is chemoheterotrophic, deriving its energy from organic compounds. Observations indicate that it can exist in various arrangements, including chains, pairs, and singles, and it possesses flagella, contributing to its mobility. The strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, suggesting a close association with human hosts. Klebsiella pneumoniae strain 53 has a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans, indicating its adaptability and potential for cross-species transmission. This bacterium is associated with multiple health effects, often leading to serious infections such as bacteremia, pneumonia, urinary tract infections, and sepsis. The presence of Klebsiella pneumoniae strain 53 in clinical settings underscores its pathogenic potential, particularly in immunocompromised individuals or those with underlying health conditions. In terms of ecological insights, the strain’s ability to exist as free-living organisms while also being pathogenic highlights its dual nature. This adaptability may allow it to persist in various environments, including human hosts and other organisms, potentially facilitating the spread of antibiotic resistance and complicating public health responses.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain 53

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain 53
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain 53 contig825, whole genome shotgun

Gene Summary

Adenine Count

1406286 bp

Thymine Count

1403122 bp

Guanine Count

1784758 bp

Cytosine Count

1801619 bp

Genome Length

6455857 bp

Protein-coding Genes

6499 genes

Non-Coding Genes

234 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Site-specific integraseEXT45_00285Not AvailablePositive46914 - 4724012012.6
duf1819 family proteinEXT45_00290Not AvailableNegative47428 - 476679244.1
Trna-asn;Not AvailableNot AvailablePositive47855 - 47930Not Available
Hypothetical proteinEXT45_00295Not AvailableNegative48286 - 4857310582.2
Hypothetical proteinEXT45_00300Not AvailableNegative48854 - 491269858.92
Trna-ser;Not AvailableNot AvailablePositive48922 - 49011Not Available
hypothetical proteinEXT45_00305Not AvailableNegative49210 - 494167656.52
hypothetical proteinEXT45_00310Not AvailableNegative49718 - 499127339.11
Hypothetical proteinEXT45_00315Not AvailableNegative49915 - 5051121878.0
Hypothetical proteinEXT45_00320Not AvailableNegative50595 - 5107717521.4

Displaying genes 11 – 20 of 6744 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total