Klebsiella pneumoniae strain KP14CR KP14CR_74

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain KP14CR (accession SETP00000000.1) is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism as a chemoheterotroph. This strain is characterized by its motility, facilitated by the presence of flagella, and typically arranges itself in chains, pairs, or singles. KP14CR thrives optimally at 37°C, classifying it as mesophilic. This bacterium is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and vertebrates. Its pathogenicity in humans is of significant concern, as it is linked to a wide range of health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis. Other notable conditions caused by KP14CR include intra-abdominal infections, liver abscesses, and neonatal sepsis. The ecological role of KP14CR is noteworthy, as it exists in a free-living biotic relationship while being capable of opportunistic infections in a variety of hosts. This versatility in habitat and pathogenicity highlights the potential for Klebsiella pneumoniae to adapt and thrive in diverse environments, including human-associated niches. The bacterium’s ability to cause serious infections, particularly in immunocompromised individuals, points to the broader implications of Klebsiella pneumoniae in public health and the importance of monitoring its prevalence in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain KP14CR KP14CR_74

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain KP14CR KP14CR_74
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain KP14CR KP14CR_74, whole genome

Gene Summary

Adenine Count

1178859 bp

Thymine Count

1181288 bp

Guanine Count

1570229 bp

Cytosine Count

1588470 bp

Genome Length

5524433 bp

Protein-coding Genes

5190 genes

Non-Coding Genes

257 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Cp4-57 prophageEWP64_06655Not AvailableNegative1291527 - 129272044787.7
Tmrna,resume;Not AvailableNot AvailablePositive1292916 - 1293278Not Available
Ssra-binding proteinEWP64_06665Not AvailableNegative1293423 - 129390518240.1
Type ii toxin-antitoxin system toxin rataEWP64_06670Not AvailablePositive1294016 - 129449217439.3
Rnfh family proteinEWP64_06675Not AvailablePositive1294482 - 129477210835.1
Outer membrane protein assembly factor bameEWP64_06680Not AvailableNegative1294839 - 129518012414.0
Dna repair protein recnEWP64_06685Not AvailableNegative1295328 - 129698961364.2
Dna repair protein recnEWP64_06690Not AvailableNegative1297076 - 129795432410.0
hypotheticalEWP64_06695Not AvailablePositive1297943 - 12980824817.12
Heat shock proteinEWP64_06700Not AvailablePositive1298079 - 129866921751.9

Displaying genes 11 – 20 of 5448 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total