Klebsiella pneumoniae strain KP14CR KP14CR_74

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain KP14CR (accession SETP00000000.1) is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism as a chemoheterotroph. This strain is characterized by its motility, facilitated by the presence of flagella, and typically arranges itself in chains, pairs, or singles. KP14CR thrives optimally at 37°C, classifying it as mesophilic. This bacterium is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and vertebrates. Its pathogenicity in humans is of significant concern, as it is linked to a wide range of health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis. Other notable conditions caused by KP14CR include intra-abdominal infections, liver abscesses, and neonatal sepsis. The ecological role of KP14CR is noteworthy, as it exists in a free-living biotic relationship while being capable of opportunistic infections in a variety of hosts. This versatility in habitat and pathogenicity highlights the potential for Klebsiella pneumoniae to adapt and thrive in diverse environments, including human-associated niches. The bacterium’s ability to cause serious infections, particularly in immunocompromised individuals, points to the broader implications of Klebsiella pneumoniae in public health and the importance of monitoring its prevalence in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain KP14CR KP14CR_74

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain KP14CR KP14CR_74
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain KP14CR KP14CR_74, whole genome

Gene Summary

Adenine Count

1178859 bp

Thymine Count

1181288 bp

Guanine Count

1570229 bp

Cytosine Count

1588470 bp

Genome Length

5524433 bp

Protein-coding Genes

5190 genes

Non-Coding Genes

257 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
exodeoxyribonuclease iiiEWP64_19265Not AvailablePositive3811754 - 381256030899.6
tvp38/tmem64 family proteinEWP64_19270Not AvailablePositive3812774 - 381343023739.5
tvp38/tmem64 family proteinEWP64_19275Not AvailablePositive3813417 - 381412725428.5
carboxymuconolactone decarboxylase family proteinEWP64_19280Not AvailablePositive3814124 - 381468420717.1
abc transporter substrate-binding proteinEWP64_19285Not AvailablePositive3814687 - 381586543210.4
thiamine abc transporter permeaseEWP64_19290Not AvailablePositive3815838 - 381639520063.2
abc transporter permease subunitEWP64_19295Not AvailablePositive3816396 - 381738335123.8
atp-binding cassette domain-containing proteinEWP64_19300Not AvailablePositive3817383 - 381801523362.3
sulfurtransferaseEWP64_19305Not AvailablePositive3818109 - 381941647950.5
cdp-alcohol phosphatidyltransferase family proteinEWP64_19310Not AvailableNegative3819468 - 382009122036.2

Displaying genes 3781 – 3790 of 5448 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total