Enterobacter cloacae strain GEN000188

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain GEN000188 is a gram-negative, facultative anaerobic bacterium characterized by its rod shape and the presence of flagella, which is indicative of its motility capabilities. This strain is mesophilic, thriving within moderate temperature ranges. Genetically, it possesses one replicon and features a double-membrane structure typical of gram-negative bacteria. This strain is known to inhabit multiple environments, displaying a free-living biotic relationship. It has been identified in various hosts, including humans (Homo sapiens), cattle (Bos), and the okapi (Okapia johnstoni). Enterobacter cloacae is recognized for its pathogenicity in humans, being associated with several serious health conditions such as vertebral osteomyelitis, bacteremia, spondylodiscitis, and various bloodstream and urinary and respiratory tract infections. The presence of Enterobacter cloacae strain GEN000188 in both human and animal hosts underscores its ecological versatility and potential as an opportunistic pathogen. Its ability to thrive in diverse environments, coupled with its pathogenic potential, highlights the importance of monitoring this bacterium in clinical and ecological contexts to mitigate its health impacts. The strain's genetic accession number is SEKG00000000.1, which provides a reference for further studies on its characteristics and implications in health and disease.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain GEN000188

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain GEN000188
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain GEN000188

Gene Summary

Adenine Count

1114301 bp

Thymine Count

1116099 bp

Guanine Count

1376537 bp

Cytosine Count

1375162 bp

Genome Length

4990206 bp

Protein-coding Genes

4497 genes

Non-Coding Genes

334 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase foldEVY09_12940Not AvailableNegative2710432 - 271129830921.4
type 1 fimbrial protein subunit fimaEVY09_12945Not AvailablePositive2711608 - 271217119224.4
type 1 fimbrial protein subunit fimiEVY09_12950Not AvailablePositive2712241 - 271278319320.1
molecular chaperone fimcEVY09_12955Not AvailablePositive2712818 - 271351024822.1
outer membrane usher protein fimdEVY09_12960Not AvailablePositive2713525 - 271608393212.8
type 1 fimbrin d-mannose specific adhesin fimhEVY09_12965Not AvailablePositive2716076 - 271708336260.1
fimbriae assembly proteinEVY09_12970Not AvailablePositive2717093 - 271761418423.6
fimbriae biosynthesis transcriptional regulator fimzEVY09_12975Not AvailableNegative2717665 - 271829723399.7
response regulator transcription factorEVY09_12980Not AvailableNegative2719106 - 271982227636.2
eal domain-containing proteinEVY09_12985Not AvailableNegative2719847 - 272050924647.8

Displaying genes 2821 – 2830 of 4833 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total