Escherichia coli strain GEN000185

Escherichia coli strain GEN000185 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile, possessing flagella that facilitate movement. It typically resides in host-associated habitats, with an optimal growth temperature of 37°C, classifying it as mesophilic. The strain has a single replicon and features a double membrane structure characteristic of Gram-negative bacteria. It has a diverse array of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates, indicating its widespread ecological presence and adaptability. E. coli strain GEN000185 is associated with numerous health effects, particularly in humans. It is recognized for its role in urinary tract infections (UTIs), gastrointestinal infections, and conditions such as neonatal meningitis, septicemia, and foodborne illnesses. The strain is implicated in serious health issues including hemolytic uremic syndrome (HUS), renal failure, and various types of enteric diseases. Its pathogenicity highlights its potential to cause significant clinical challenges, especially in vulnerable populations. The ecological insight derived from the diverse host range and associated health effects suggests that E. coli strain GEN000185 plays a critical role in both human health and agricultural contexts. Its presence in multiple species indicates its adaptability and potential impact on food safety and public health, emphasizing the need for continued monitoring and research into its pathogenic capabilities.