Escherichia coli strain 42_rectal

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 42_rectal is a Gram-negative, rod-shaped bacterium characterized by its mobility and the presence of flagella. This strain is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. It has a unique cellular arrangement, typically found in singles or pairs, and possesses a single replicon with a double membrane structure. This strain has a wide range of hosts, including various mammals such as Homo sapiens, Bos taurus, and Sus scrofa, as well as non-mammalian hosts like Solanum lycopersicum and Apis mellifera. Its adaptability to diverse hosts indicates a significant ecological versatility, allowing it to establish in both terrestrial and aquatic environments. E. coli strain 42_rectal is associated with numerous health effects, particularly in humans. It is known to cause urinary tract infections (UTIs), gastrointestinal diseases, and severe conditions such as neonatal meningitis and septicemia. Additionally, it is implicated in foodborne infections, with potential to lead to serious complications like hemolytic uremic syndrome (HUS) and renal failure. The strain exemplifies a complex biotic relationship as it is free-living yet pathogenic in certain contexts. Its ability to inhabit various hosts while also being linked to significant health concerns highlights the dual nature of E. coli as both a commensal and a pathogen. This duality underscores the importance of understanding microbial interactions within host ecosystems, particularly in the context of health and disease management.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 42_rectal

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 42_rectal
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 42_rectal

Gene Summary

Adenine Count

1325138 bp

Thymine Count

1326980 bp

Guanine Count

1359154 bp

Cytosine Count

1352967 bp

Genome Length

5374076 bp

Protein-coding Genes

4877 genes

Non-Coding Genes

364 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nad(p)h nitroreductaseEPS91_14455Not AvailablePositive3038986 - 303953720073.2
selenide, water dikinase seldEPS91_14460Not AvailablePositive3039654 - 304069736674.5
dna topoisomerase iiiEPS91_14465Not AvailablePositive3040702 - 304265773157.0
nadp-specific glutamate dehydrogenaseEPS91_14470Not AvailableNegative3042734 - 304407748558.1
duf1496 domain-containing proteinEPS91_14475Not AvailablePositive3044313 - 30445859928.93
pyrimidine (deoxy)nucleoside triphosphate diphosphataseEPS91_14480Not AvailableNegative3044551 - 304495815056.0
cdp-alcohol phosphatidyltransferase family proteinEPS91_14485Not AvailablePositive3045045 - 304566522597.9
abc transporter permeaseEPS91_14500Not AvailableNegative3047481 - 304901656163.0
abc transporter substrate-binding proteinEPS91_14505Not AvailableNegative3048989 - 305015542962.8
carboxymuconolactone decarboxylase family proteinEPS91_14510Not AvailableNegative3050165 - 305071320612.2

Displaying genes 3091 – 3100 of 5255 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total