Escherichia coli strain 46_rectal

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 46_rectal is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is notable for its mobility, facilitated by the presence of flagella, and typically exists in pairs or as single cells. It is classified as mesophilic, with an optimal growth temperature of 37°C. This strain is primarily host-associated, indicating a close relationship with various organisms, including Homo sapiens, Gallus gallus, and Bos taurus, among others. It has been identified in a wide range of hosts, including mammals, birds, and even some plants, such as Solanum lycopersicum and Brassica oleracea var. italica. The extensive diversity in hosts suggests that strain 46_rectal may play significant roles in various ecological niches, potentially influencing host health and microbiota composition. E. coli strain 46_rectal is associated with numerous health effects, particularly affecting the urinary and gastrointestinal systems. It is implicated in conditions like urinary tract infections (UTIs), gastrointestinal infections, and more severe outcomes such as septicemia and hemolytic uremic syndrome (HUS). The strain’s pathogenicity in humans highlights its potential as a significant public health concern, particularly in foodborne infections and nosocomial settings. The multifaceted interactions between E. coli strain 46_rectal and its diverse host organisms present an important insight into its ecological role. Strain 46_rectal’s ability to thrive in various environments and its association with disease underline its significance in both microbiological research and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 46_rectal

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 46_rectal
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 46_rectal

Gene Summary

Adenine Count

1287439 bp

Thymine Count

1292544 bp

Guanine Count

1328816 bp

Cytosine Count

1304181 bp

Genome Length

5217173 bp

Protein-coding Genes

4820 genes

Non-Coding Genes

289 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nark family nitrate/nitrite mfs transporterEPS94_19445Not AvailablePositive4000782 - 400217349696.3
nitrate reductase subunit alphaEPS94_19450Not AvailablePositive4002566 - 4006309140597.0
nitrate reductase subunit betaEPS94_19455Not AvailablePositive4006306 - 400784458083.6
nitrate reductase molybdenum cofactor assembly chaperoneEPS94_19460Not AvailablePositive4007841 - 400855126450.3
respiratory nitrate reductase subunit gammaEPS94_19465Not AvailablePositive4008551 - 400922825484.9
is4 family transposaseEPS94_19470Not AvailableNegative4009281 - 401048045856.9
Trna-tyrNot AvailableNot AvailablePositive4010911 - 4010995Not Available
Trna-tyrNot AvailableNot AvailablePositive4011029 - 4011113Not Available
Trna-tyrNot AvailableNot AvailablePositive4011119 - 4011200Not Available
formyltetrahydrofolate deformylaseEPS94_19495Not AvailableNegative4011360 - 401220231922.6

Displaying genes 3941 – 3950 of 5118 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total