Escherichia coli strain 52_rectal

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 52_rectal is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and possesses flagella, indicating its motility. This strain is primarily host-associated, found in various hosts including Homo sapiens, Gallus gallus, Bos taurus, and others across diverse taxa, such as Metazoa and Vertebrata. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range, which is ideal for growth in warm-blooded animals. E. coli strain 52_rectal has significant pathogenic potential, being associated with a wide array of health effects, particularly in humans. It is implicated in urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain can contribute to diverse clinical manifestations, including diarrhea, septicemia, and even colorectal cancer. The presence of such a broad spectrum of pathogenicity highlights its relevance in both clinical and public health contexts. The ecological role of E. coli strain 52_rectal as a free-living organism suggests it can thrive independently in various environments, potentially influencing microbial communities. Its association with numerous hosts underscores its adaptability and ability to spread across different ecological niches, which may have implications for infection control and understanding the dynamics of microbial transmission in both animal and human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 52_rectal

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 52_rectal
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 52_rectal


Gene Summary

Adenine Count

1279593 bp

Thymine Count

1283389 bp

Guanine Count

1320483 bp

Cytosine Count

1307343 bp

Genome Length

5200701 bp

Protein-coding Genes

4728 genes

Non-Coding Genes

404 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
trna lysidine(34) synthetase tilsEPT01_02500Not AvailableNegative478232 - 47953048206.9
voc family proteinEPT01_02505Not AvailableNegative479595 - 47998414737.4
lysine decarboxylase ldccEPT01_02510Not AvailableNegative480041 - 48218280594.9
acetyl-coa carboxylase carboxyl transferase subunit alphaEPT01_02515Not AvailableNegative482281 - 48324035243.6
dna polymerase iii subunit alphaEPT01_02520Not AvailableNegative483253 - 486735129912.0
ribonuclease hiiEPT01_02525Not AvailableNegative486772 - 48736821517.2
lipid-a-disaccharide synthaseEPT01_02530Not AvailableNegative487365 - 48851342384.9
acyl-acp--udp-n-acetylglucosamine o-acyltransferaseEPT01_02535Not AvailableNegative488513 - 48930128081.7
3-hydroxyacyl-acp dehydratase fabzEPT01_02540Not AvailableNegative489305 - 48976017034.0
udp-3-o-(3-hydroxymyristoyl)glucosamine n-acyltransferaseEPT01_02545Not AvailableNegative489865 - 49089036040.7

Displaying genes 811 – 820 of 5134 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total