Escherichia coli strain 52_rectal

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 52_rectal is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and possesses flagella, indicating its motility. This strain is primarily host-associated, found in various hosts including Homo sapiens, Gallus gallus, Bos taurus, and others across diverse taxa, such as Metazoa and Vertebrata. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range, which is ideal for growth in warm-blooded animals. E. coli strain 52_rectal has significant pathogenic potential, being associated with a wide array of health effects, particularly in humans. It is implicated in urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain can contribute to diverse clinical manifestations, including diarrhea, septicemia, and even colorectal cancer. The presence of such a broad spectrum of pathogenicity highlights its relevance in both clinical and public health contexts. The ecological role of E. coli strain 52_rectal as a free-living organism suggests it can thrive independently in various environments, potentially influencing microbial communities. Its association with numerous hosts underscores its adaptability and ability to spread across different ecological niches, which may have implications for infection control and understanding the dynamics of microbial transmission in both animal and human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 52_rectal

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 52_rectal
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 52_rectal


Gene Summary

Adenine Count

1279593 bp

Thymine Count

1283389 bp

Guanine Count

1320483 bp

Cytosine Count

1307343 bp

Genome Length

5200701 bp

Protein-coding Genes

4728 genes

Non-Coding Genes

404 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinEPT01_24530Not AvailablePositive4869603 - 487020522652.7
Nine proteinEPT01_24535Not AvailablePositive4870202 - 48702793273.0
Hypothetical proteinEPT01_24540Not AvailablePositive4870387 - 487143639054.3
Dna-binding protein roiEPT01_24545Not AvailablePositive4871588 - 487231026941.6
Hypothetical proteinEPT01_24550Not AvailablePositive4872310 - 487291523765.4
Gene 59 proteinEPT01_24555Not AvailablePositive4872959 - 487347719724.2
Trna,type:pseudo,anti_codon:gtt;Not AvailableNot AvailablePositive4873541 - 4873615Not Available
Putative terbEPT01_24560Not AvailablePositive4873784 - 487421515748.8
Hypothetical proteinEPT01_24565Not AvailablePositive4874212 - 48743765719.51
Hypothetical proteinEPT01_24570Not AvailableNegative4874672 - 487500712796.7

Displaying genes 331 – 340 of 5134 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

315 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da

Displaying 1–10 of 315 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total