Staphylococcus capitis strain H8

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Staphylococcaceae

Genus

Staphylococcus

Description

Staphylococcus capitis strain H8 is a Gram-positive cocci bacterium primarily associated with neonatal intensive care units (NICUs), as well as being found on the skin surface of humans and in pork meat. As a facultative anaerobe, this bacterium can thrive in both aerobic and anaerobic environments, making it versatile in various habitats. This strain possesses a single replicon and is characterized by the presence of flagella, which may contribute to its motility and ability to colonize different surfaces. S. capitis strain H8 is of particular concern in healthcare settings due to its association with several serious health effects, including septicaemia, bloodstream infections, sepsis, skin infections, and septic meningitis. These infections often fall under the category of healthcare-acquired infections (HAIs), posing significant risks to vulnerable populations, such as neonates in NICUs. Given its ability to inhabit human skin and its potential to cause severe infections, S. capitis strain H8 underscores the importance of stringent hygiene practices in healthcare environments to mitigate the risk of HAIs. The bacterium's adaptability to diverse environments, coupled with its pathogenic potential, highlights the need for ongoing surveillance and research to understand its behavior and impact in both clinical and ecological contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyStaphylococcaceae
GenusStaphylococcus
SpeciesStaphylococcus capitis
Strainstrain H8

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Staphylococcus capitis strain H8
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatneonatal intensive care units (NICUs); pork meat; skin; skin surface of the foot
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Staphylococcus capitis strain H8

Gene Summary

Adenine Count

984490 bp

Thymine Count

988589 bp

Guanine Count

476781 bp

Cytosine Count

479765 bp

Genome Length

2971439 bp

Protein-coding Genes

3257 genes

Non-Coding Genes

75 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf1806 family proteinEQ811_00275Not AvailableNegative56265 - 5663313904.4
glucosamine-6-phosphate deaminaseEQ811_00280Not AvailablePositive57176 - 5791627798.9
3-hexulose-6-phosphate synthaseEQ811_00285Not AvailablePositive58016 - 5864822421.8
6-phospho-3-hexuloisomeraseEQ811_00290Not AvailablePositive58650 - 5919820023.7
had family hydrolaseEQ811_00295Not AvailablePositive59319 - 5996624766.5
long-chain fatty acid--coa ligaseEQ811_00300Not AvailablePositive60079 - 6143451486.3
thiolase family proteinEQ811_00305Not AvailablePositive61437 - 6257641520.2
protein vracEQ811_00310Not AvailablePositive62551 - 6291614807.1
hypothetical proteinEQ811_00315Not AvailablePositive62918 - 6317810180.5
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinaseEQ811_00330Not AvailableNegative67092 - 6792229927.7

Displaying genes 61 – 70 of 3331 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

252 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 252 metabolites

Health Effects

Health ConditionRelationReference
Healthcare-acquired infectionsCausesPMC6437968
HaisCausesPMC6437968
SepticaemiaCausesPMC8393854
Septic meningitisCausesPMC8393854
Skin infectionsCausesPMC9392311
Bloodstream infectionsCausesPMC9392311
SepsisCausesPMC9392311

Displaying health effects 1 – 7 of 7 in total