Escherichia coli strain EC117

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain EC117 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and demonstrates mobility due to the presence of flagella. It typically thrives at an optimal temperature of 37°C, placing it within the mesophilic temperature range. This strain is characterized by a free-living biotic relationship and is primarily host-associated, indicating its reliance on various hosts for survival. EC117 has a wide host range, including Homo sapiens, various livestock (e.g., Bos taurus, Sus scrofa), and other vertebrates such as Aves and Canis lupus familiaris. Additionally, it can associate with multiple plant species, indicating its ecological versatility. The strain has a single replicon and is surrounded by two membranes, a trait common to Gram-negative bacteria. Clinically, E. coli strain EC117 is associated with numerous health effects in humans and other hosts. It is implicated in urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's ability to cause these diseases highlights its pathogenic potential, particularly in relation to enteric and urinary tract health. The ecological insight from this data suggests that E. coli strain EC117 plays a significant role in both health and disease across a diverse range of hosts. Its adaptability and pathogenicity underline the importance of monitoring and understanding this strain in public health and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain EC117

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain EC117
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain EC117 NODE_155_length_209_cov_10.9268,

Gene Summary

Adenine Count

1333875 bp

Thymine Count

1330962 bp

Guanine Count

1359319 bp

Cytosine Count

1378844 bp

Genome Length

5414605 bp

Protein-coding Genes

4929 genes

Non-Coding Genes

297 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-binding protein ybibEQ825_14740Not AvailablePositive3063957 - 306491935050.7
malate/lactate/ureidoglycolate dehydrogenaseEQ825_14745Not AvailablePositive3065060 - 306614538861.3
duf1471 domain-containing proteinEQ825_14750Not AvailableNegative3066374 - 30666348568.2
dksa/trar family c4-type zinc finger proteinEQ825_14755Not AvailableNegative3066900 - 30671669804.42
fe2+-dependent dioxygenaseEQ825_14760Not AvailableNegative3067240 - 306791725530.2
catecholate siderophore receptor fiuEQ825_14765Not AvailableNegative3067959 - 307024181927.4
duf1471 domain-containing proteinEQ825_14770Not AvailableNegative3070506 - 30707668896.65
23s rrna (adenine(1618)-n(6))-methyltransferase rlmfEQ825_14775Not AvailablePositive3070937 - 307196838358.9
mechanosensitive channel proteinEQ825_14780Not AvailableNegative3071965 - 307419082007.6
glutamine abc transporter atp-binding protein glnqEQ825_14785Not AvailableNegative3074451 - 307517326733.6

Displaying genes 2991 – 3000 of 5240 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total