Neisseria gonorrhoeae strain GC-190

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-190 is a Gram-negative, cocci-shaped bacterium that is primarily associated with human hosts (Homo sapiens) and other mammals (Mammalia). It exhibits a cell arrangement of singles and pairs, indicating its typical morphology in clinical samples. This strain is categorized as an aerobe, requiring oxygen for growth, and thrives optimally at a temperature of 35°C, placing it within the mesophilic temperature range. N. gonorrhoeae strain GC-190 possesses two membranes and a single replicon, characteristics typical of its genus. Notably, it lacks motility, as it does not have flagella, which is consistent with the non-motile nature of many Neisseria species. Despite being classified as free-living, its primary biotic interactions occur within host organisms. This strain is clinically significant, associated with a range of health effects including gonorrhea, septicemia, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections. The presence of N. gonorrhoeae in human populations underscores its role in public health concerns, particularly due to its impact on sexual health and potential complications if left untreated. In summary, Neisseria gonorrhoeae strain GC-190 exemplifies a pathogen that is well-adapted to its host-associated habitat, with specific traits that facilitate its survival and transmission. Its clinical relevance highlights the importance of ongoing monitoring and research to address the challenges posed by this organism in human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-190

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-190
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-190

Gene Summary

Adenine Count

515018 bp

Thymine Count

511645 bp

Guanine Count

563242 bp

Cytosine Count

566660 bp

Genome Length

2165416 bp

Protein-coding Genes

2222 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
is1595 family transposaseEPH56_12800Not AvailablePositive2149404 - 214969410440.8
opacity protein opa54EPH56_12805Not AvailableNegative2149695 - 214998511060.9
t cell/b cell stimulating protein tspbEPH56_12810Not AvailableNegative2149986 - 215027311263.4
t cell/b cell stimulating protein tspbEPH56_12815Not AvailablePositive2150274 - 215056111664.1
transposaseEPH56_12820Not AvailablePositive2150562 - 215084610341.3
is1595 family transposaseEPH56_12825Not AvailableNegative2150847 - 21511269800.86
hypothetical proteinEPH56_12830Not AvailableNegative2151127 - 21513588544.85
duf1020 domain-containing proteinEPH56_12835Not AvailableNegative2151406 - 215168310298.4
replication initiation factorEPH56_12840Not AvailableNegative2151937 - 21521829213.83
pilinEPH56_12855Not AvailablePositive2152598 - 21526582487.03

Displaying genes 2301 – 2310 of 2317 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total