Neisseria gonorrhoeae strain GC-190

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-190 is a Gram-negative, cocci-shaped bacterium that is primarily associated with human hosts (Homo sapiens) and other mammals (Mammalia). It exhibits a cell arrangement of singles and pairs, indicating its typical morphology in clinical samples. This strain is categorized as an aerobe, requiring oxygen for growth, and thrives optimally at a temperature of 35°C, placing it within the mesophilic temperature range. N. gonorrhoeae strain GC-190 possesses two membranes and a single replicon, characteristics typical of its genus. Notably, it lacks motility, as it does not have flagella, which is consistent with the non-motile nature of many Neisseria species. Despite being classified as free-living, its primary biotic interactions occur within host organisms. This strain is clinically significant, associated with a range of health effects including gonorrhea, septicemia, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections. The presence of N. gonorrhoeae in human populations underscores its role in public health concerns, particularly due to its impact on sexual health and potential complications if left untreated. In summary, Neisseria gonorrhoeae strain GC-190 exemplifies a pathogen that is well-adapted to its host-associated habitat, with specific traits that facilitate its survival and transmission. Its clinical relevance highlights the importance of ongoing monitoring and research to address the challenges posed by this organism in human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-190

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-190
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-190

Gene Summary

Adenine Count

515018 bp

Thymine Count

511645 bp

Guanine Count

563242 bp

Cytosine Count

566660 bp

Genome Length

2165416 bp

Protein-coding Genes

2222 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
s-formylglutathione hydrolaseEPH56_07465Not AvailablePositive1283164 - 128399131428.1
cell division protein zapeEPH56_07470Not AvailablePositive1284521 - 128567243771.4
nucleoside-diphosphate kinaseEPH56_07475Not AvailablePositive1285731 - 128615615441.6
23s rrna (adenine(2503)-c(2))-methyltransferase rlmnEPH56_07480Not AvailablePositive1286300 - 128739441074.6
type iv pilus biogenesis/stability protein pilwEPH56_07485Not AvailablePositive1287397 - 128815828453.0
flavodoxin-dependent (e)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthaseEPH56_07490Not AvailablePositive1288174 - 128943945370.9
atp-dependent clp protease proteolytic subunitEPH56_07495Not AvailableNegative1289493 - 129010722607.2
trigger factorEPH56_07500Not AvailableNegative1290203 - 129151648412.6
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/gtp cyclohydrolase iiEPH56_07515Not AvailablePositive1292611 - 129370239231.4
abc transporterEPH56_07520Not AvailableNegative1293865 - 12940025042.29

Displaying genes 1441 – 1450 of 2317 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total