Neisseria gonorrhoeae strain GC-214

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-214 is a Gram-negative, coccoid bacterium that is primarily host-associated, with Homo sapiens and Mammalia as its main hosts. This strain is classified as an aerobe, requiring the presence of oxygen for survival and growth. It exists in a cell arrangement of singles or pairs and does not exhibit mobility, as it lacks flagella. GC-214 has a mesophilic temperature range, thriving optimally at 35°C, which aligns with the typical human body temperature, facilitating its role as a human pathogen. This strain is characterized by having a single replicon and two membranes, a trait common among Gram-negative bacteria. In terms of health effects, N. gonorrhoeae strain GC-214 is known to cause a range of conditions, including gonorrhea, septicemia, eye infections such as conjunctivitis, male urethritis, and disseminated gonococcal infections. Its pathogenic capabilities highlight its importance in human health, particularly in sexually transmitted infections. Understanding the traits of Neisseria gonorrhoeae strain GC-214 provides insight into its ecological role as a free-living organism within the human host environment. The bacterium's ability to thrive under specific conditions and its pathogenic relationships underscore the need for continued research and public health measures to address the diseases it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-214

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-214
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-214

Gene Summary

Adenine Count

511228 bp

Thymine Count

509170 bp

Guanine Count

558477 bp

Cytosine Count

564679 bp

Genome Length

2151080 bp

Protein-coding Genes

2203 genes

Non-Coding Genes

91 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
leucyl/phenylalanyl-trna--protein transferaseEPH54_01180Not AvailableNegative203560 - 20428526902.2
ferric iron uptake transcriptional regulatorEPH54_01185Not AvailableNegative204355 - 20478916411.5
fur family transcriptional regulatorEPH54_01190Not AvailableNegative204855 - 2050015319.61
outer membrane protein assembly factor bameEPH54_01195Not AvailablePositive205016 - 20539313953.8
4-hydroxy-tetrahydrodipicolinate reductaseEPH54_01200Not AvailablePositive205403 - 20621228270.8
hypothetical proteinEPH54_01205Not AvailableNegative206326 - 20663112160.4
lipid-a-disaccharide synthaseEPH54_01210Not AvailableNegative206852 - 20802443066.9
rlua family pseudouridine synthaseEPH54_01215Not AvailableNegative208175 - 20916736663.9
rne/rng family ribonucleaseEPH54_01225Not AvailablePositive209660 - 212419101700.0
4-hydroxythreonine-4-phosphate dehydrogenase pdxaEPH54_01230Not AvailableNegative212649 - 21364134532.8

Displaying genes 281 – 290 of 2294 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total