Neisseria gonorrhoeae strain GC-211

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-211 is a Gram-negative cocci bacterium primarily associated with human hosts (Homo sapiens) and certain mammals (Mammalia). This strain exhibits a characteristic cell arrangement of singles and pairs, which is typical for this species. As an aerobe, it requires oxygen for growth and thrives optimally at a temperature of 35°C, indicating it is mesophilic in nature. N. gonorrhoeae GC-211 is non-motile and does not possess flagella, which is consistent with the general behavior of Neisseria species. The bacterium has a complex structure, featuring two membranes and a single replicon, which are indicative of its Gram-negative classification. The health effects associated with this strain are significant, as it is responsible for various conditions, including gonorrhea, septicemia, and eye infections such as conjunctivitis. It can also lead to male urethritis and disseminated gonococcal infections, impacting both individual health and public health systems. From an ecological perspective, N. gonorrhoeae strain GC-211's ability to exist in a free-living state, despite primarily being host-associated, suggests a degree of adaptability. Its pathogenic potential in humans highlights the importance of understanding its biological traits to develop effective treatment and prevention strategies. The presence of this strain in human populations underscores the ongoing need for vigilance in addressing sexually transmitted infections and their complications.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-211

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-211
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-211

Gene Summary

Adenine Count

511287 bp

Thymine Count

509518 bp

Guanine Count

557449 bp

Cytosine Count

566143 bp

Genome Length

2152029 bp

Protein-coding Genes

2197 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulator foliEPH51_00925Not AvailablePositive156044 - 15648416494.1
bifunctional tetrahydrofolate synthase/dihydrofolate synthaseEPH51_00930Not AvailablePositive156515 - 15778946420.6
cell division protein ftsnEPH51_00935Not AvailablePositive157803 - 15884337008.0
cvpa family proteinEPH51_00940Not AvailablePositive158836 - 15933317550.7
amidophosphoribosyltransferaseEPH51_00945Not AvailablePositive159527 - 16107155920.6
transcription elongation factor grebEPH51_00950Not AvailablePositive161171 - 16166218595.2
phosphoribosylanthranilate isomeraseEPH51_00955Not AvailablePositive161721 - 16234722546.0
lactoferrin/transferrin family tonb-dependent receptorEPH51_00960Not AvailableNegative162821 - 165652105660.0
transferrin-binding protein-like solute binding proteinEPH51_00965Not AvailableNegative165649 - 16763473238.9
lactoferrin-binding proteinEPH51_00970Not AvailableNegative167597 - 1678097460.93

Displaying genes 241 – 250 of 2292 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total