Neisseria gonorrhoeae strain GC-195

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-195 is a Gram-negative bacterium characterized by its cocci shape and arrangement typically found in singles and pairs. This strain is strictly aerobic, requiring oxygen for growth, and is mesophilic, with an optimal temperature of 35°C, which aligns with the body temperature of its hosts. It possesses a unique cellular structure consisting of two membranes and has one replicon. Notably, Neisseria gonorrhoeae GC-195 lacks mobility and does not have flagella. The primary habitat of this strain is host-associated, predominantly within Homo sapiens and other Mammalia. It exhibits a free-living biotic relationship, indicating that while it thrives within a host, it can also exist outside of a host organism under certain conditions. N. gonorrhoeae strain GC-195 is known to cause several health issues in humans, including septicemia, gonorrhea, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections. The significant health effects associated with this strain highlight its role as a pathogen in human populations. The ability to cause a range of infections, particularly sexually transmitted diseases, underscores the importance of understanding its biology and ecology for public health. Given its wide host range and pathogenic potential, Neisseria gonorrhoeae strain GC-195 serves as an important subject for ongoing research in microbiology and infectious disease prevention.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-195

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-195
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-195

Gene Summary

Adenine Count

522374 bp

Thymine Count

522901 bp

Guanine Count

578543 bp

Cytosine Count

568339 bp

Genome Length

2204983 bp

Protein-coding Genes

2294 genes

Non-Coding Genes

93 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEPH36_01045Not AvailablePositive178610 - 17898113719.5
atp-binding cassette domain-containing proteinEPH36_01050Not AvailablePositive179058 - 18098071834.5
duf4124 domain-containing proteinEPH36_01055Not AvailablePositive181006 - 18136212633.2
hypothetical proteinEPH36_01060Not AvailablePositive181453 - 18196518460.2
hypothetical proteinEPH36_01065Not AvailablePositive182013 - 1821896928.63
duf4400 domain-containing proteinEPH36_01070Not AvailableNegative182410 - 18310526401.8
type iv conjugative transfer system coupling protein tradEPH36_01075Not AvailableNegative183095 - 18513775863.7
conjugal transfer protein traiEPH36_01080Not AvailableNegative185134 - 18768694649.0
hypothetical proteinEPH36_01085Not AvailableNegative187683 - 18810216214.4
lytic transglycosylaseEPH36_01090Not AvailablePositive188612 - 18907317077.8

Displaying genes 261 – 270 of 2386 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total