Neisseria gonorrhoeae strain GC-195

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-195 is a Gram-negative bacterium characterized by its cocci shape and arrangement typically found in singles and pairs. This strain is strictly aerobic, requiring oxygen for growth, and is mesophilic, with an optimal temperature of 35°C, which aligns with the body temperature of its hosts. It possesses a unique cellular structure consisting of two membranes and has one replicon. Notably, Neisseria gonorrhoeae GC-195 lacks mobility and does not have flagella. The primary habitat of this strain is host-associated, predominantly within Homo sapiens and other Mammalia. It exhibits a free-living biotic relationship, indicating that while it thrives within a host, it can also exist outside of a host organism under certain conditions. N. gonorrhoeae strain GC-195 is known to cause several health issues in humans, including septicemia, gonorrhea, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections. The significant health effects associated with this strain highlight its role as a pathogen in human populations. The ability to cause a range of infections, particularly sexually transmitted diseases, underscores the importance of understanding its biology and ecology for public health. Given its wide host range and pathogenic potential, Neisseria gonorrhoeae strain GC-195 serves as an important subject for ongoing research in microbiology and infectious disease prevention.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-195

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-195
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-195

Gene Summary

Adenine Count

522374 bp

Thymine Count

522901 bp

Guanine Count

578543 bp

Cytosine Count

568339 bp

Genome Length

2204983 bp

Protein-coding Genes

2294 genes

Non-Coding Genes

93 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
restriction endonuclease subunit sEPH36_06730Not AvailablePositive1168864 - 117006645586.8
hypothetical proteinEPH36_06735Not AvailablePositive1170059 - 117061921980.0
hypothetical proteinEPH36_06740Not AvailablePositive1170630 - 117146932626.1
sam-dependent dna methyltransferaseEPH36_06745Not AvailablePositive1171536 - 117313760101.8
abc transporterEPH36_06750Not AvailablePositive1173148 - 11732855042.29
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/gtp cyclohydrolase iiEPH36_06755Not AvailableNegative1173448 - 117453939231.4
transposaseEPH36_06765Not AvailablePositive1175235 - 11754418113.84
bcct family transporterEPH36_06770Not AvailablePositive1175620 - 117760274370.6
fatty acid--coa ligaseEPH36_06775Not AvailableNegative1177691 - 117924457524.8
gdsl family lipaseEPH36_06780Not AvailableNegative1179495 - 118068842623.6

Displaying genes 1301 – 1310 of 2386 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total